Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Republic of Korea.
J Plast Reconstr Aesthet Surg. 2012 Dec;65(12):1627-31. doi: 10.1016/j.bjps.2012.06.008. Epub 2012 Jul 2.
Prominent signs of ageing of the hands have recently been treated with permanent or longer-lasting injectable dermal fillers. However, few previous studies have described the long-term complications of such hand rejuvenation. The purpose of our report was to share our experience of 15 cases with long-term complications following hand rejuvenation using various medical fillers.
We performed a retrospective review of the management of 15 patients who presented with complications from the injection of synthetic fillers for hand rejuvenation at a tertiary medical centre over a period of 10 years from March 2002 to January 2011.
Injected materials included polymethylmethacrylate (PMMA) microsphere filler, calcium hydroxyapatite filler, hyaluronic acid filler, poly-l-lactic acid (PLLA) filler and other medical fillers. Of the total study sample of 15 patients, nine underwent surgical excision, six patients with a history of PMMA or PLLA filler injection received intralesional steroid therapy and three patients with a history of hyaluronic acid filler injection received injection therapy using hyaluronidase.
Hand rejuvenation complications can be successfully treated according to our proposed algorithm.
手部老化的明显迹象最近已采用永久性或更持久的可注射真皮填充剂进行治疗。然而，以前很少有研究描述过这种手部年轻化的长期并发症。我们报告的目的是分享我们在使用各种医用填充物进行手部年轻化治疗后出现长期并发症的 15 例经验。
我们对 2002 年 3 月至 2011 年 1 月期间在三级医疗中心接受过用于手部年轻化的合成填充物注射后出现并发症的 15 名患者进行了回顾性研究。
注射的材料包括聚甲基丙烯酸甲酯（PMMA）微球填充物、钙羟磷灰石填充物、透明质酸填充物、聚左旋乳酸（PLLA）填充物和其他医用填充物。在总共 15 名患者的研究样本中，9 名患者接受了手术切除，6 名有 PMMA 或 PLLA 填充物注射史的患者接受了病灶内类固醇治疗，3 名有透明质酸填充物注射史的患者接受了透明质酸酶注射治疗。
根据我们提出的算法，可以成功治疗手部年轻化并发症。
