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英国胆囊息肉样病变的治疗和监测。

Treatment and surveillance of polypoid lesions of the gallbladder in the United Kingdom.

机构信息

Hepatopancreatobiliary and Transplant Unit, St James' Hospital, Leeds, UK.

出版信息

HPB (Oxford). 2012 Jul;14(7):435-40. doi: 10.1111/j.1477-2574.2012.00471.x. Epub 2012 May 11.

Abstract

OBJECTIVES

The increase in the routine use of abdominal imaging has led to a parallel surge in the identification of polypoid lesions in the gallbladder. True gallbladder polyps (GBP) have malignant potential and surgery can prevent or treat early gallbladder cancer. In an era of constraint on health care resources, it is important to ensure that surgery is offered only to patients who have appropriate indications. The aim of this study was to assess treatment and surveillance policies for GBP among hepatobiliary and upper gastrointestinal tract surgeons in the UK in the light of published evidence.

METHODS

A questionnaire on the management of GBP was devised and sent to consultant surgeon members of the Association of Upper Gastrointestinal Surgeons (AUGIS) of Great Britain and Ireland with the approval of the AUGIS Committee. It included eight questions on indications for laparoscopic cholecystectomy and surveillance based on GBP (size, number, growth rate) and patient (age, comorbidities, ethnicity) characteristics.

RESULTS

A total of 79 completed questionnaires were returned. The vast majority of surgeons (>75%) stated that they would perform surgery when a single GBP reached 10 mm in size. However, there was a lack of uniformity in the management of multiple polyps and polyp growth rate, with different surveillance protocols for patients treated conservatively.

CONCLUSIONS

Gallbladder polyps are a relatively common finding on abdominal ultrasound scans. The survey showed considerable heterogeneity among surgeons regarding treatment and surveillance protocols. Although no randomized controlled trials exist, national guidelines would facilitate standardization, the formulation of an appropriate algorithm and appropriate use of resources.

摘要

目的

腹部影像学常规应用的增加导致胆囊息肉样病变的检出率也相应增高。真正的胆囊息肉(GBP)有恶变的可能,手术可以预防或治疗早期胆囊癌。在医疗资源受到限制的时代,确保仅向有适当适应证的患者提供手术非常重要。本研究旨在根据已发表的证据,评估英国肝胆和上消化道外科医生对 GBP 的治疗和监测政策。

方法

在得到英国上消化道外科医师协会(AUGIS)委员会的批准后,我们设计并向该协会的顾问外科医生成员发送了一份关于 GBP 管理的调查问卷,其中包括八项关于腹腔镜胆囊切除术适应证和基于 GBP(大小、数量、生长速度)和患者(年龄、合并症、种族)特征的监测问题。

结果

共收回 79 份完整的调查问卷。绝大多数外科医生(>75%)表示,当单个 GBP 达到 10mm 时,他们将进行手术。然而,对于多发性息肉和息肉生长速度的管理缺乏一致性,对于接受保守治疗的患者有不同的监测方案。

结论

胆囊息肉是腹部超声扫描的一种常见发现。该调查显示,外科医生在治疗和监测方案方面存在相当大的异质性。尽管没有随机对照试验,但国家指南将有助于标准化、制定适当的算法和合理利用资源。

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