Le Saux A, Poli Merol M L, Zachar D, Josset P, Pezzettigotta S, Doco Fenzy M, Guyot E, Francois-Fiquet C
Pediatric Surgical Unit, American Memorial Hospital, CHU Reims, France.
Int J Pediatr Otorhinolaryngol. 2012 Aug;76(8):1225-7. doi: 10.1016/j.ijporl.2012.05.011. Epub 2012 Jun 4.
We report two original cases of association of cleft palate and lateral cervico-facial teratoma. We discuss the embryological explanation. The first child presented a cleft palate associated with two cervico-facial localisations of teratoma. The other had Pierre Robin sequence associated with lateropharyngeal teratoma with an extra sub maxillary localisation. Most reported cases were of midline teratomas, leading different authors to advance a mechanical origin to the cleft. Our cases are different: we could hardly find reported cases of associate lateral tumours and cleft palate, which would suggest two different embryologic mechanisms, or at least a combination of more complicated phenomenons.
我们报告了两例腭裂与颈部面部外侧畸胎瘤相关的原始病例。我们讨论了胚胎学解释。第一个孩子表现为腭裂伴有两个颈部面部畸胎瘤定位。另一个患有皮埃尔·罗宾序列征，伴有咽外侧畸胎瘤及额外的颌下定位。大多数报道的病例是中线畸胎瘤，导致不同作者提出腭裂的机械性起源。我们的病例不同：我们几乎找不到报道的外侧肿瘤与腭裂相关的病例，这表明存在两种不同的胚胎学机制，或者至少是更复杂现象的组合。
