Roszkiewicz J, Roszkiewicz A, Szarmach H
Katedry i Kliniki Chorób Skórnych i Wenerycznych w Gdańsku.
Przegl Dermatol. 1990 Jul-Aug;77(4):241-8.
The alterations in the ultrastructural feature of Langerhans cells in patients with allergic contact eczema were characterized by significant increase in number of Birbeck granules accompanied by the increase in volume of smooth- and rough-surfaced endoplasmic reticulum. These changes may be regarded as a morphological expression of the increase of the synthetic and secretory activity of the Langerhans cells. In the epidermis the Langerhans cells associated with immediately adjacent precursor cells (the so called indeterminate cells), lymphoid cells and keratinocytes form the morphologically visible and probably functional units.
过敏性接触性湿疹患者朗格汉斯细胞超微结构特征的改变表现为伯贝克颗粒数量显著增加，同时伴有滑面和粗面内质网体积增大。这些变化可被视为朗格汉斯细胞合成和分泌活性增加的形态学表现。在表皮中，朗格汉斯细胞与紧邻的前体细胞（即所谓的未定型细胞）、淋巴细胞和角质形成细胞形成形态上可见且可能具有功能的单位。
