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[外伤性眼损伤后托洛萨-亨特综合征]

[Tolosa-Hunt syndrome following traumatic eye injury].

作者信息

Granados-Reyes Gema M, Soriano-Redondo Elisa, Duran-Ferreras Eduardo

机构信息

Hospital Infanta Elena, Huelva, Spain.

出版信息

Rev Neurol. 2012 Jun 16;54(12):729-33.

Abstract

INTRODUCTION

Tolosa-Hunt syndrome (THS) is an idiopathic condition involving unilateral eye pain with involvement of oculomotor nerves which responds well to treatment with steroids. It is produced by idiopathic granulomatous inflammation of the cavernous sinus or the orbital apex.

CASE REPORT

A 37-year-old male who was admitted to hospital due to a six-week history of blurred vision and pain in the left eye, which was later accompanied by full ipsilateral ophthalmoplegia. Some days prior to the onset of the clinical features, he suffered an accident which resulted in traumatic injury to the left eye. An examination showed data pointing to optic neuropathy in the left eye with complete extrinsic ocular motor palsy. Results of general analyses and lumbar puncture were normal. Magnetic resonance imaging (MRI) of the head revealed a thickening of the wall of the left cavernous sinus and of the ipsilateral orbital apex, which enhanced with gadolinium. Evoked potential studies showed axonal and demyelinating optic neuropathy on the left-hand side. Suspecting this to be a case of THS, treatment was established with high doses of corticoids, which brought about an improvement in the pain and eye movement but not in the blurred vision. A MRI control scan showed a clear improvement in comparison to the one carried out initially.

CONCLUSIONS

In cases of painful ophthalmoplegia, the professional should suspect the existence of THS. If the apex of the orbit is affected through the superior orbital fissure, the optic nerve may be damaged. Traumatic injury can be one of the situations that trigger THS.

摘要

引言

托洛萨-亨特综合征(THS)是一种特发性疾病,表现为单侧眼痛并累及动眼神经,对类固醇治疗反应良好。它由海绵窦或眶尖的特发性肉芽肿性炎症引起。

病例报告

一名37岁男性因左眼视力模糊和疼痛6周入院,随后出现同侧完全性眼肌麻痹。在临床症状出现前几天,他发生了一起事故,导致左眼外伤。检查显示有数据指向左眼视神经病变并伴有完全性眼外肌麻痹。常规分析和腰椎穿刺结果正常。头部磁共振成像(MRI)显示左侧海绵窦壁和同侧眶尖增厚,钆增强扫描有强化。诱发电位研究显示左侧存在轴索性和脱髓鞘性视神经病变。怀疑这是一例THS,遂采用大剂量皮质类固醇进行治疗,疼痛和眼球运动有所改善,但视力模糊症状未改善。MRI对照扫描显示与最初的扫描相比有明显改善。

结论

在出现疼痛性眼肌麻痹的病例中,医生应怀疑存在THS。如果眶尖通过眶上裂受到影响,视神经可能会受损。外伤可能是引发THS的情况之一。

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