Spinner T, Segerer M, Holub A, Spes C, Mudra H
Klinik für Kardiologie, Pneumologie und Internistische Intensivmedizin, Klinikum München GmbH, Klinikum Neuperlach, Oscar-Maria-Graf-Ring 51, 81737, München, Deutschland.
Internist (Berl). 2012 Aug;53(8):985-9. doi: 10.1007/s00108-012-3082-x.
We describe the case of a 24-year-old woman who was admitted to the emergency department with dyspnea and sinus tachycardia. The suspected diagnosis of pulmonary embolism was confirmed by computed tomography (CT) scan. The patient lost consciousness soon afterwards and was found to be pulseless. Cardiopulmonary resuscitation was performed and high dosis thrombolysis was given. The patient survived without sequelae and was discharged on oral anticoagulation from the hospital 8 days after the initial admission. In our opinion unknown factor-V Leiden in combination with a local form of hormonal contraception (NuvaRing®) was responsible for the deep venous thrombosis of the left leg and the pulmonary embolism.
我们描述了一名24岁女性的病例，她因呼吸困难和窦性心动过速被收入急诊科。计算机断层扫描（CT）证实了疑似肺栓塞的诊断。此后不久患者失去意识，被发现无脉搏。进行了心肺复苏并给予了大剂量溶栓治疗。患者存活且无后遗症，在首次入院8天后口服抗凝药出院。我们认为，未知的凝血因子V莱顿突变与局部使用的激素避孕药（优悦婷®）共同导致了左腿深静脉血栓形成和肺栓塞。
