Suppr超能文献

癌症患者分子靶向治疗中肠毒性的影像学特征。

Imaging features of bowel toxicities in the setting of molecular targeted therapies in cancer patients.

机构信息

Department of Imaging, Dana-Farber Cancer Institute, Boston, MA, USA.

出版信息

Br J Radiol. 2012 Oct;85(1018):1420-6. doi: 10.1259/bjr/19815818. Epub 2012 Jun 6.

Abstract

Molecular targeted therapies are becoming ubiquitous in cancer treatment. These drugs may cause gastrointestinal toxicities including perforation, pneumatosis, enteritis, colitis and fistula formation. Knowledge of these complications and their management enables early radiological identification and appropriate intervention, reducing patient morbidity and mortality.

摘要

分子靶向治疗在癌症治疗中变得无处不在。这些药物可能会引起胃肠道毒性,包括穿孔、气肿、肠炎、结肠炎和瘘管形成。了解这些并发症及其处理方法可以实现早期放射学识别和适当的干预,从而降低患者的发病率和死亡率。

相似文献

1
Imaging features of bowel toxicities in the setting of molecular targeted therapies in cancer patients.
Br J Radiol. 2012 Oct;85(1018):1420-6. doi: 10.1259/bjr/19815818. Epub 2012 Jun 6.
3
Reply: To PMID 23169717.
AJR Am J Roentgenol. 2013 Aug;201(2):W370. doi: 10.2214/AJR.13.10818.
4
Portal venous gas secondary to molecular targeted therapy.
AJR Am J Roentgenol. 2013 Aug;201(2):W368-9. doi: 10.2214/AJR.13.10770.
5
Gastrointestinal complications following renal transplantation.
Radiology. 1975 Oct;117(1):37-43. doi: 10.1148/117.1.37.
6
Education and imaging. Gastrointestinal: Benign cause for pneumatosis intestinalis and portomesenteric venous gas.
J Gastroenterol Hepatol. 2009 May;24(5):927. doi: 10.1111/j.1440-1746.2009.05886.x.
7
Pneumatosis Intestinalis After Molecular-Targeted Therapy.
World Neurosurg. 2019 May;125:312-315. doi: 10.1016/j.wneu.2019.01.225. Epub 2019 Feb 11.
9
Pneumatosis cystoides intestinalis: case report and review of literature.
Clin J Gastroenterol. 2020 Feb;13(1):31-36. doi: 10.1007/s12328-019-00999-3. Epub 2019 Jun 3.

引用本文的文献

2
Imaging of abdominopelvic oncologic emergencies.
Abdom Radiol (NY). 2024 Mar;49(3):823-841. doi: 10.1007/s00261-023-04112-8. Epub 2023 Nov 28.
3
Selpercatinib Treatment of RET-Mutated Thyroid Cancers Is Associated With Gastrointestinal Adverse Effects.
J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3824-e3829. doi: 10.1210/clinem/dgac337.
4
Pneumatosis Intestinalis Induced by Anticancer Treatment: A Systematic Review.
Cancers (Basel). 2022 Mar 25;14(7):1666. doi: 10.3390/cancers14071666.
6
Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian Cancer.
Clin Pract Cases Emerg Med. 2020 Mar 27;4(2):227-229. doi: 10.5811/cpcem.2020.1.45374. eCollection 2020 May.
7
Diarrhea Concealing a Duodenal-Cecal Fistula Secondary to Appendiceal Mucinous Neoplasm.
ACG Case Rep J. 2017 Jan 4;4:e3. doi: 10.14309/crj.2017.3. eCollection 2017.
8
Evolving Cancer Classification in the Era of Personalized Medicine: A Primer for Radiologists.
Korean J Radiol. 2017 Jan-Feb;18(1):6-17. doi: 10.3348/kjr.2017.18.1.6. Epub 2017 Jan 5.
9
Pneumatosis intestinalis after gefitinib therapy for pulmonary adenocarcinoma: a case report.
World J Surg Oncol. 2016 Jun 29;14(1):175. doi: 10.1186/s12957-016-0926-1.
10
Update on the role of imaging in management of metastatic colorectal cancer.
Radiographics. 2014 Nov-Dec;34(7):1908-28. doi: 10.1148/rg.347130090.

本文引用的文献

2
Everolimus- and temsirolimus-associated enteritis: report of three cases.
J Clin Oncol. 2011 May 10;29(14):e404-6. doi: 10.1200/JCO.2010.33.5984. Epub 2011 Feb 28.
3
Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences.
J Comput Assist Tomogr. 2011 Jan-Feb;35(1):86-90. doi: 10.1097/RCT.0b013e3181fce2cb.
5
Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review.
Angiogenesis. 2011 May;14(2):135-41. doi: 10.1007/s10456-010-9197-6. Epub 2010 Dec 29.
6
Improved survival with ipilimumab in patients with metastatic melanoma.
N Engl J Med. 2010 Aug 19;363(8):711-23. doi: 10.1056/NEJMoa1003466. Epub 2010 Jun 5.
8
Which factors predict bowel complications in patients with recurrent epithelial ovarian cancer being treated with bevacizumab?
Gynecol Oncol. 2010 Jul;118(1):47-51. doi: 10.1016/j.ygyno.2010.01.011. Epub 2010 Apr 10.
10
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis.
Lancet Oncol. 2009 Jun;10(6):559-68. doi: 10.1016/S1470-2045(09)70112-3.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验