Department of Imaging, Dana-Farber Cancer Institute, Boston, MA, USA.
Br J Radiol. 2012 Oct;85(1018):1420-6. doi: 10.1259/bjr/19815818. Epub 2012 Jun 6.
Molecular targeted therapies are becoming ubiquitous in cancer treatment. These drugs may cause gastrointestinal toxicities including perforation, pneumatosis, enteritis, colitis and fistula formation. Knowledge of these complications and their management enables early radiological identification and appropriate intervention, reducing patient morbidity and mortality.
分子靶向治疗在癌症治疗中变得无处不在。这些药物可能会引起胃肠道毒性,包括穿孔、气肿、肠炎、结肠炎和瘘管形成。了解这些并发症及其处理方法可以实现早期放射学识别和适当的干预,从而降低患者的发病率和死亡率。