McCarthy Christopher James, Roberts Christopher, Gittins Matthew, Oldham Jacqueline Ann
Physiotherapy, Imperial College Healthcare, London, UK.
Physiother Res Int. 2012 Jun;17(2):92-100. doi: 10.1002/pri.517. Epub 2011 Aug 26.
Non-specific low back pain (NSLBP) accounts for over 85% of all low back pain. Homogenous subgroups may exist within this diagnosis. This study derived a clinical examination and evaluated the examination's ability to identify homogenous subgroups in NSLBP.
Patients with NSLBP were examined using a standardized clinical examination. Each patient was examined by two physiotherapists. Data were analysed for item reliability and the presence of distinct subgroups using cluster analysis. Cross-validation of the clusters identified was conducted.
Three hundred and one patients were examined. The inter-tester reliability of the majority of items was moderate to substantial (52% of items with kappa > 0.40). A K-means cluster analysis of the two data sets revealed agreement on the presence of two subgroups. One group (n = 47, 16%) had higher fear avoidance beliefs, anxiety and disability. They were more likely to be provoked by pain provocative tests. They were also more likely to be judged as having central sensitization and a dominant psychosocial component to their presentation.
The identification of a group of hypervigilant NSLBP patients should allow the interventions to be targeted towards this group. A valid, standardized clinical examination does contribute to the diagnostic management of NSLBP.
非特异性下腰痛(NSLBP)占所有下腰痛的85%以上。在这一诊断中可能存在同质亚组。本研究进行了一项临床检查,并评估了该检查识别NSLBP同质亚组的能力。
采用标准化临床检查对NSLBP患者进行检查。每位患者由两名物理治疗师进行检查。使用聚类分析对数据进行项目可靠性和不同亚组存在情况的分析。对所识别的聚类进行交叉验证。
共检查了301例患者。大多数项目的检查者间信度为中度至高度(52%的项目kappa>0.40)。对两个数据集进行K均值聚类分析,结果显示存在两个亚组。一组(n = 47,16%)具有较高的恐惧回避信念、焦虑和残疾程度。他们更有可能因疼痛激发试验而被激发。他们也更有可能被判定为存在中枢敏化,且其临床表现具有主要的心理社会成分。
识别出一组高度警觉的NSLBP患者应能使干预措施针对该组患者。有效的标准化临床检查确实有助于NSLBP的诊断管理。