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1
Is heel prick as safe as we think?足跟采血和我们想象的一样安全吗?
BMJ Case Rep. 2011 Oct 16;2011:bcr0820114677. doi: 10.1136/bcr.08.2011.4677.
2
Assessment of Neonatal Pain During Heel Prick: Lancet vs Needle-A Randomized Controlled Study.足跟采血时新生儿疼痛的评估:柳叶刀采血法与针头采血法的随机对照研究
J Trop Pediatr. 2017 Oct 1;63(5):346-351. doi: 10.1093/tropej/fmw093.
3
Purulent lymphadenitis caused by Staphylococcus argenteus, representing the first Japanese case of Staphylococcus argenteus (multilocus sequence type 2250) infection in a 12-year-old boy.由银色葡萄球菌引起的化脓性淋巴结炎,这是日本首例银色葡萄球菌(多位点序列类型2250)感染病例,患者为一名12岁男孩。
J Infect Chemother. 2018 Nov;24(11):925-927. doi: 10.1016/j.jiac.2018.03.018. Epub 2018 Apr 27.
4
Topical amethocaine gel for pain relief of heel prick blood sampling: a randomised double blind controlled trial.外用丁卡因凝胶用于足跟采血疼痛缓解的随机双盲对照试验。
Arch Dis Child Fetal Neonatal Ed. 2001 Jan;84(1):F56-9. doi: 10.1136/fn.84.1.f56.
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Flatfoot and calcaneal deformity secondary to osteomyelitis after neonatal heel puncture.
J Pediatr Orthop B. 1999 Apr;8(2):122-4.
6
Venipuncture versus heel prick for blood glucose monitoring in neonates.静脉穿刺与足跟采血用于新生儿血糖监测的比较。
Singapore Med J. 2009 Oct;50(10):1004-7.
7
Comparative heel stick study showed that newborn infants who had undergone repeated painful procedures showed increased short-term pain responses.足跟采血对比研究表明,经历过多次疼痛操作的新生儿表现出更强的短期疼痛反应。
Acta Paediatr. 2016 Nov;105(11):e520-e525. doi: 10.1111/apa.13557.
8
Effect of Kangaroo mother care in reducing pain due to heel prick among preterm neonates: a crossover trial.袋鼠式护理对减轻早产儿足跟采血疼痛的效果:一项交叉试验。
J Matern Fetal Neonatal Med. 2014 Mar;27(5):488-90. doi: 10.3109/14767058.2013.818974. Epub 2013 Jul 18.
9
The knowledge level of the healthcare professionals responsible for newborns' heel prick tests.负责新生儿足跟采血检测的医护人员的知识水平。
J Pediatr Nurs. 2024 Sep-Oct;78:133-141. doi: 10.1016/j.pedn.2024.06.011. Epub 2024 Jun 26.
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[The effect of two different methods of heel lancing on pain reaction in preterm neonates].[两种不同足跟采血方法对早产儿疼痛反应的影响]
Assist Inferm Ric. 1999 Oct-Dec;18(4):185-92.

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Neonatal Kidney Function, Injury and Drug Dosing: A Contemporary Review.新生儿肾功能、损伤与药物剂量:当代综述
Children (Basel). 2025 Mar 7;12(3):339. doi: 10.3390/children12030339.
2
Application of machine learning algorithms for accurate determination of bilirubin level on in vitro engineered tissue phantom images.机器学习算法在体外工程组织模型图像上准确测定胆红素水平的应用。
Sci Rep. 2024 Mar 12;14(1):5952. doi: 10.1038/s41598-024-56319-4.
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Indications, Measurements, and Complications of Ten Essential Neonatal Procedures.十种基本新生儿操作的适应症、测量方法及并发症
Int J Pediatr. 2023 Sep 5;2023:3241607. doi: 10.1155/2023/3241607. eCollection 2023.

本文引用的文献

1
Neonatal staphylococcal scalded skin syndrome: clinical and outbreak containment review.新生儿葡萄球菌性烫伤样皮肤综合征:临床和暴发控制回顾。
Eur J Pediatr. 2010 Dec;169(12):1503-9. doi: 10.1007/s00431-010-1252-1. Epub 2010 Jul 13.
2
Late onset group B streptococcal disease manifested by isolated cervical lymphadenitis.以孤立性颈淋巴结炎为表现的晚发型B族链球菌病
Arch Dis Child. 2003 Nov;88(11):1019-20. doi: 10.1136/adc.88.11.1019.
3
Group B streptococcal retropharyngeal cellulitis in a young infant: a case report and review of the literature.一名幼儿的B族链球菌咽后蜂窝织炎:病例报告及文献复习
J Emerg Med. 2002 Aug;23(2):179-82. doi: 10.1016/s0736-4679(02)00489-4.
4
Retropharyngeal cellulitis in a 5-week-old infant.
Pediatrics. 2002 Mar;109(3):E51. doi: 10.1542/peds.109.3.e51.
5
Outbreak of staphylococcal infections following heel puncture for blood sampling.足跟采血后葡萄球菌感染暴发。
Am J Dis Child. 1981 Mar;135(3):277-8. doi: 10.1001/archpedi.1981.02130270069025.
6
Neonatal osteomyelitis of the calcaneus: complication of heel puncture.
J Pediatr. 1976 Mar;88(3):478-80. doi: 10.1016/s0022-3476(76)80272-7.

足跟采血和我们想象的一样安全吗?

Is heel prick as safe as we think?

作者信息

Onesimo Roberta, Fioretti Maria, Pili Stefania, Monaco Serena, Romagnoli Costantino, Fundarò Carlo

机构信息

Pediatrics Department, Catholic University of Sacred Heart, Rome, Italy.

出版信息

BMJ Case Rep. 2011 Oct 16;2011:bcr0820114677. doi: 10.1136/bcr.08.2011.4677.

DOI:10.1136/bcr.08.2011.4677
PMID:22675035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3207768/
Abstract

Purulent lymphadenitis is rare in newborn and is associated with prematurity and invasive procedure. Neonatal staphylococcal infections due to skin interruption during intramuscular vitamin K administration and national metabolic screening programme (heel prick or Guthrie card test) have been already previously described. This is a report of a premature infant who developed an inguinal adenitis as a result of late complications from heel pricks. The diagnosis was made on clinical grounds and confirmed by ultrasound scans. Staphylococcus aureus was isolated. Bacteremia did not occur and the lymphadenitis had a complete resolution with antimicrobial therapy. The heel prick is a well-established procedure in neonatal practice, nevertheless it is not risk-free. The attention to signs of infections is important to avoid complications such as purulent lymphadenitis, abscess formation and septicemia. Best practice prevention and control in minimising the risk of infections are the most important intervention to prevent this complication.

摘要

脓性淋巴结炎在新生儿中罕见,与早产和侵入性操作有关。先前已有关于因肌肉注射维生素K期间皮肤破损以及国家代谢筛查项目(足跟采血或古思里卡片试验)导致新生儿葡萄球菌感染的报道。本文报告了一名早产儿因足跟采血的晚期并发症而发生腹股沟淋巴结炎的病例。根据临床症状做出诊断,并经超声扫描确诊。分离出金黄色葡萄球菌。未发生菌血症,经抗菌治疗后淋巴结炎完全消退。足跟采血是新生儿科常用的操作,但并非没有风险。关注感染迹象对于避免脓性淋巴结炎、脓肿形成和败血症等并发症很重要。最佳的预防和控制措施以降低感染风险是预防该并发症的最重要干预手段。