Gois Carlos, Dias Vasco V, Raposo João F, do Carmo Isabel, Barbosa Antonio
Department of Psychiatry, Faculty of Medicine, University of Lisbon, Santa Maria Hospital, Av, Professor Egas Moniz, Lisbon 1600, Portugal.
BMC Res Notes. 2012 Jun 7;5:271. doi: 10.1186/1756-0500-5-271.
Vulnerability to stress has been associated to distress, emotional distress symptoms and metabolic control in type 2 diabetes mellitus (T2DM) patients as well. Furthermore some conflicting results were noticed. We aimed to evaluate the effect over metabolic control in what concerns vulnerability to stress beyond depressive and anxiety symptoms.
This cross-sectional study assessed 273 T2DM patients with depressive and anxiety symptoms using the Hospital Anxiety Depression Scale (HADS) and the 23 Questions to assess Vulnerability to Stress (23QVS), along with demographic and clinical diabetes-related variables. Hierarchical logistic regression models were used to investigate predictors of poor glycemic control. The results showed an association of depressive symptoms (odds ratio = 1.12, 95%CI = 1.01-1.24, P = 0.030) with increased risk of poor glycemic control. Anxiety symptoms and vulnerability to stress on their own were not predictive of metabolic control, respectively (odds ratio = 0.92, 95%CI = 0.84-1.00, P = 0.187 and odds ratio = 0.98, 95%CI = 0.95-1.01, P = 0.282).
Our data suggested that vulnerability to stress was not predictive of poor glycemic control in T2DM, but depressive symptoms were.
压力易感性也与2型糖尿病（T2DM）患者的痛苦、情绪困扰症状及代谢控制有关。此外，还发现了一些相互矛盾的结果。我们旨在评估压力易感性对代谢控制的影响，这涉及到除抑郁和焦虑症状之外的压力易感性。
这项横断面研究使用医院焦虑抑郁量表（HADS）和23个压力易感性问题评估量表（23QVS）对273名有抑郁和焦虑症状的T2DM患者进行了评估，同时收集了人口统计学和糖尿病相关临床变量。采用分层逻辑回归模型研究血糖控制不佳的预测因素。结果显示，抑郁症状（比值比=1.12，95%置信区间=1.01-1.24，P=0.030）与血糖控制不佳风险增加相关。焦虑症状和压力易感性本身并不能分别预测代谢控制情况（比值比=0.92，95%置信区间=0.84-1.00，P=0.187；比值比=0.98，95%置信区间=0.95-1.01，P=0.282）。
我们的数据表明，压力易感性不能预测T2DM患者血糖控制不佳，但抑郁症状可以。
