Roth S L, Horiot J C
Klinik für Strahlentherapie, Universität Düsseldorf.
Strahlenther Onkol. 1990 Dec;166(12):787-93.
Intracavitary contact radiotherapy was used according to the guidelines of J. Papillon in 91 patients with early rectal tumors (72 adenocarcinomas and 19 villous adenomas) at the Dijon Cancer Institute. Most of the patients were referred because of poor surgical risk. Ten patients had interstitial implants in addition, 96% of the patients had a complete response. The local control rate after five years was 74% (67/91). Including salvage the ultimate control rate was 91% (83/91). 85% (77/91) had preservation of the sphincter function. The size of the rectal cancer and the degree of rectal wall invasion were of prognostic impact as proposed by the clinical staging system of Dijon.
第戎癌症研究所对91例早期直肠肿瘤患者（72例腺癌和19例绒毛状腺瘤）按照J. 帕皮永的指导方针进行了腔内近距离放射治疗。大多数患者因手术风险高而转诊。另外有10例患者进行了组织间植入，96%的患者获得了完全缓解。五年后的局部控制率为74%（67/91）。包括挽救治疗在内，最终控制率为91%（83/91）。85%（77/91）的患者保留了括约肌功能。如第戎临床分期系统所提出的，直肠癌的大小和直肠壁侵犯程度具有预后意义。
