Division of Molecular Oncology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Curr Biol. 2012 Jun 5;22(11):R453-5. doi: 10.1016/j.cub.2012.04.036.
To maintain a functional and harmonious epithelial society, the number and quality of cells need to be tightly controlled. Two recent studies reveal a novel cellular process for epithelial homeostasis: crowding-mediated live cell extrusion.
为了维持功能和和谐的上皮社会,细胞的数量和质量需要被严格控制。最近的两项研究揭示了上皮细胞稳态的一种新的细胞过程:拥挤介导的活细胞挤出。