Pizova N V
Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(2 Pt 2):69-74.
Multiple sclerosis (MS) is very similar to the Sjögren's syndrome (SS) by its clinical presentations. Features found in common between the two disorders include symptoms of lesions of the brain, spinal cord and optic tract, the detection of autoantibodies, such as antinuclear, anti-Ro, anti-La and the prevalence of MRI abnormalities such as periventricular and subcortical lesions. Almost all symptoms found in patients with the CNS-SS involvement described above could be attributed to the concomitant presence of MS. Therefore, the differential diagnosis of these diseases is difficult. The paper addresses clinical and biological presentations of similarity of and differences between MS and SS in the diagnostic aspect.
多发性硬化症（MS）在临床表现上与干燥综合征（SS）非常相似。这两种疾病的共同特征包括脑、脊髓和视束病变的症状、自身抗体（如抗核抗体、抗Ro、抗La）的检测以及MRI异常（如脑室周围和皮质下病变）的发生率。几乎所有上述中枢神经系统-SS受累患者出现的症状都可归因于同时存在的MS。因此，这些疾病的鉴别诊断很困难。本文从诊断角度探讨了MS和SS在临床和生物学表现上的异同。
