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左上腔静脉异常引流至左心房与胎儿丙戊酸综合征相关。

An anomalous left superior venacava draining into left atrium in association with fetal valproate syndrome.

机构信息

Department of Neonatology, I.P.G.M.E & R. & S. S. K. M. Hospital, Kolkata, India.

出版信息

Indian J Pediatr. 2013 Jul;80(7):604-6. doi: 10.1007/s12098-012-0811-z. Epub 2012 Jun 8.

DOI:10.1007/s12098-012-0811-z
PMID:22678520
Abstract

Prenatal exposure of mother to valproic acid causes teratogenic effects on fetus. The authors report an 18 h-old girl with typical facial and limbs features of fetal valproate syndrome (FVS) along with abnormal draining of left superior vena cava into left atrium.

摘要

母亲在孕期接触丙戊酸会对胎儿造成致畸影响。作者报告了一例 18 小时大的女婴，具有典型的胎儿丙戊酸综合征（FVS）的面部和四肢特征，以及左侧上腔静脉异常引流至左心房。

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本文引用的文献

1
TERMINATION OF LEFT SUPERIOR VENA CAVA IN LEFT ATRIUM, ATRIAL SEPTAL DEFECT, AND ABSENCE OF CORONARY SINUS; A DEVELOPMENTAL COMPLEX.左上腔静脉终止于左心房、房间隔缺损及冠状窦缺如；一种发育复合体。
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Outcome of pregnancy in women attending an outpatient epilepsy clinic: adverse features associated with higher doses of sodium valproate.在门诊癫痫诊所就诊女性的妊娠结局：与高剂量丙戊酸钠相关的不良特征。
Seizure. 2002 Dec;11(8):512-8. doi: 10.1016/s1059-1311(02)00135-8.
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Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth.
产前暴露于抗癫痫药物的儿童的长期健康与神经发育
J Med Genet. 2002 Apr;39(4):251-9. doi: 10.1136/jmg.39.4.251.
4
Valproic acid embryopathy: report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature.丙戊酸胚胎病：两例同胞病例报告及表型异常的进一步扩展并文献复习
Am J Med Genet. 2001 Jan 15;98(2):168-75.
5
Evidence for multi-site closure of the neural tube in humans.人类神经管多部位闭合的证据。
Am J Med Genet. 1993 Oct 1;47(5):723-43. doi: 10.1002/ajmg.1320470528.
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Congenital anomalies in children of epileptic mothers and fathers.
Neuropediatrics. 1980 Aug;11(3):274-83. doi: 10.1055/s-2008-1071396.
7
Superior vena caval abnormalities: their occurrence rate, associated cardiac abnormalities and angiographic classification in a paediatric population with congenital heart disease.上腔静脉异常：先天性心脏病患儿群体中的发生率、相关心脏异常及血管造影分类
Clin Radiol. 1986 Mar;37(2):131-8. doi: 10.1016/s0009-9260(86)80382-8.