Okovityĭ S V, Ivkin D Iu, Malygin S V
Vestn Otorinolaringol. 2012(1):52-6.
The objective of the present work was to analyse the available pharmaceutical products used for treatment of otitis media. The rational application of these medications makes it possible to eliminate rapidly a variety of etiological factors, reduce the severity of inflammation, and improve the quality of life of the patients. One of the approaches to the achievement of these goals for the patients with otitis externa and otitis media consists of the use of combined preparations containing antibacterial, antimycotic, anti-inflammatory and analgetic components. Candibiotic is a four-components drug composed of chloramphenicol, clotrimazol, beclomethasone and lidocaine. The advantages of Candibiotic include high therapeutic efficacy due to its ethiotropic and pathogenetic activity and safety as its components do not have ototoxicity in the case of local application).
本研究的目的是分析用于治疗中耳炎的现有药品。合理使用这些药物能够迅速消除各种病因，减轻炎症的严重程度，并改善患者的生活质量。对于患有外耳道炎和中耳炎的患者，实现这些目标的方法之一是使用含有抗菌、抗真菌、抗炎和止痛成分的复方制剂。Candibiotic是一种由氯霉素、克霉唑、倍氯米松和利多卡因组成的四成分药物。Candibiotic的优点包括因其病因特异性和致病活性而具有高治疗效果，以及因其成分在局部应用时无耳毒性而具有安全性。
