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[外耳和中耳炎性疾病的局部抗菌治疗]

[Local antibacterial therapy for the inflammatory diseases of the external and middle ear].

作者信息

Khon E M, Dzhenzhera G E, Ovchinnikov A Iu

出版信息

Vestn Otorinolaringol. 2012(3):92-4.

PMID:22951697
Abstract

The objective of the present study was to estimate the efficacy and safety of candibioic designed for the treatment of the patients presenting with diffuse otitis externa and chronic otitis media. The open randomized trial included 40 patients with diffuse otitis externa and 40 ones with chronic otitis media who had undergone a surgical sanitation procedure. Their standard clinical and otorhinolaryngological examination was supplemented by the characteristic of clinical symptoms and personal complaints using the 10-score scale. The composite preparation candibiotic was found to be equally effective for the treatment of both diffuse otitis externa and chronic otitis media. The results of the study give reason to recommend the use of candibiotic as an efficacious and safe drug for the treatment of these conditions.

摘要

本研究的目的是评估用于治疗弥漫性外耳道炎和慢性中耳炎患者的坎迪比奥的疗效和安全性。这项开放随机试验纳入了40例弥漫性外耳道炎患者和40例慢性中耳炎患者,这些患者均接受了外科清洁手术。他们的标准临床和耳鼻喉科检查通过使用10分制对临床症状和个人主诉进行描述来补充。发现复方制剂坎迪比奥对弥漫性外耳道炎和慢性中耳炎的治疗同样有效。该研究结果有理由推荐将坎迪比奥作为治疗这些病症的一种有效且安全的药物。

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1
[Local antibacterial therapy for the inflammatory diseases of the external and middle ear].[外耳和中耳炎性疾病的局部抗菌治疗]
Vestn Otorinolaringol. 2012(3):92-4.
2
[Drug therapy of otitis externa and otitis media].[外耳道炎和中耳炎的药物治疗]
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[The acceleration of remission after exacerbation of chronic suppurative otitis media following functional-reconstructive operations on the middle ear].[中耳功能性重建手术后慢性化脓性中耳炎加重后缓解的加速情况]
Vestn Otorinolaringol. 2012(4):65-7.
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[Comparative characteristic of the local application of anti-inflammatory agents for the treatment of otitis externa and otitis media].
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[Efficacy of Dioxidine antimicrobial preparation for the treatment of inflammatory diseases of the external and middle ear].二氧嘧啶抗菌制剂治疗外耳和中耳炎性疾病的疗效
Vestn Otorinolaringol. 2016;81(2):61-66. doi: 10.17116/otorino201681261-66.
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[The current views of the treatment of diffuse external otitis].[弥漫性外耳道炎的当前治疗观点]
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[The comparative study of the of clinical effectiveness of the Candibiotic, Otipax, and Anauran ear drops for the treatment of acute external and middle ear otitis].[坎迪比奥、奥蒂帕克和阿瑙兰耳滴剂治疗急性外耳道炎和中耳炎临床疗效的比较研究]
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[Treatment of chronic otitis media in continuous or recurrent purulent discharge].[持续性或复发性脓性分泌物慢性中耳炎的治疗]
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The development of antibiotic resistant organisms with the use of ototopical medications.使用耳局部用药导致抗生素耐药菌的产生。
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Curr Med Res Opin. 2004 Aug;20(8):1175-83. doi: 10.1185/030079902125004312.

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