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2
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Complete remission of nephrotic syndrome of hepatitis B virus-associated membranous glomerulopathy after lamivudine monotherapy.拉米夫定单药治疗后乙肝病毒相关性膜性肾小球病所致肾病综合征完全缓解
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Another case of HBV associated membranous glomerulonephritis resolving on lamivudine.另一例乙型肝炎病毒相关性膜性肾小球肾炎经拉米夫定治疗后痊愈。
Arch Dis Child. 2003 May;88(5):460. doi: 10.1136/adc.88.5.460.

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A consensus statement on the renal monitoring of Australian patients receiving tenofovir based antiviral therapy for HIV/HBV infection.关于澳大利亚接受基于替诺福韦的抗逆转录病毒治疗的HIV/HBV感染患者肾脏监测的共识声明。
AIDS Res Ther. 2014 Nov 10;11:35. doi: 10.1186/1742-6405-11-35. eCollection 2014.
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本文引用的文献

1
Hepatitis B virus-associated nephropathy: an International Data Analysis.乙型肝炎病毒相关性肾病：一项国际数据分析
Iran J Kidney Dis. 2010 Apr;4(2):101-5.
2
Variant of hepatitis B virus with primary resistance to adefovir.对阿德福韦具有原发性耐药性的乙型肝炎病毒变异株
N Engl J Med. 2006 Apr 27;354(17):1807-12. doi: 10.1056/NEJMoa051214.
3
Lamivudine for the treatment of membranous glomerulopathy secondary to chronic Hepatitis B infection.拉米夫定治疗慢性乙型肝炎感染继发的膜性肾小球病。
Can J Gastroenterol. 2005 Oct;19(10):625-9. doi: 10.1155/2005/378587.
4
Lamivudine in hepatitis B-associated membranous nephropathy.拉米夫定治疗乙型肝炎相关性膜性肾病。
Kidney Int. 2005 Oct;68(4):1750-8. doi: 10.1111/j.1523-1755.2005.00591.x.
5
Tenofovir in chronic hepatitis B.替诺福韦治疗慢性乙型肝炎
Hepatology. 2005 May;41(5):1199-200; author reply 1200. doi: 10.1002/hep.20693.
6
Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment.与核苷类逆转录酶抑制剂治疗相比，富马酸替诺福韦二吡呋酯治疗相关的肾功能变化。
Clin Infect Dis. 2005 Apr 15;40(8):1194-8. doi: 10.1086/428840. Epub 2005 Mar 17.
7
Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection.阿德福韦与替诺福韦治疗拉米夫定耐药乙型肝炎病毒感染的比较。
Hepatology. 2004 Dec;40(6):1421-5. doi: 10.1002/hep.20464.
8
Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.阿德福韦酯治疗乙肝e抗原阳性慢性乙型肝炎。
N Engl J Med. 2003 Feb 27;348(9):808-16. doi: 10.1056/NEJMoa020681.
9
Role of interferon-alpha in the treatment of primary glomerulonephritis.α干扰素在原发性肾小球肾炎治疗中的作用
Am J Kidney Dis. 1999 Jun;33(6):1142-6. doi: 10.1016/s0272-6386(99)70153-8.
10
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy.长期拉米夫定治疗期间YMDD基序突变型乙型肝炎病毒的出现与取代以及治疗停止后野生型病毒的重新取代
Hepatology. 1998 Jun;27(6):1711-6. doi: 10.1002/hep.510270634.

拉米夫定和替诺福韦治疗乙型肝炎病毒相关性膜性肾小球肾炎及蛋白尿

Hepatitis B virus related membranous glomerulonephritis and proteinuria treated with lamivudine and tenofovir.

作者信息

Das Partha, Vivek Vadamalai, Ford Martin, Kingdon Edward, Holt Stephen

机构信息

Department of Nephrology and Transplantation, Guy and St Thomas Hospitals, NHS Foundation Trust, London, UK.

出版信息

BMJ Case Rep. 2011 Aug 31;2011:bcr0520114287. doi: 10.1136/bcr.05.2011.4287.

DOI:10.1136/bcr.05.2011.4287
PMID:22679045
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3176360/
Abstract

Membranous glomerulonephritis is the most common histological renal lesion associated with hepatitis B virus (HBV) infection. The authors describe here a case of a patient presenting with the nephrotic syndrome and HBV infection but without progressive liver disease. The use of lamivudine and tenofovir resulted in arrest of proteinuria and stabilisation of renal function.

摘要

膜性肾小球肾炎是与乙型肝炎病毒（HBV）感染相关的最常见的组织学肾脏病变。作者在此描述了一例表现为肾病综合征和HBV感染但无进行性肝病的患者。使用拉米夫定和替诺福韦导致蛋白尿停止和肾功能稳定。