Ramasamy Anantharaman, Patel Chiraush, Conlon Christopher
Department of Acute General Medicine, John Radcliffe Hospital, Oxford, UK.
BMJ Case Rep. 2011 Oct 4;2011:bcr0820114568. doi: 10.1136/bcr.08.2011.4568.
Steven-Johnson syndrome is a common condition characterised by erythematous target lesions on the skin and involvement of the oral mucosa, genitals and conjunctivae. It has been documented as one of the extra-pulmonary manifestations of Mycoplasma pneumoniae infection. Recently, there has been several documentation of an incomplete presentation of this syndrome - without the typical rash but with mucosal, conjunctival and genital involvement. Our case illustrates that the incomplete Steven-Johnson syndrome may present with oral mucosal and conjunctival involvement alone without skin or genital involvement. This important clinical diagnosis should not be missed due to its atypical presentation. Treatment of Steven-Johnson syndrome remains supportive along with treating the underlying infection if recognised.
史蒂文斯-约翰逊综合征是一种常见病症,其特征为皮肤上出现红斑性靶形损害,并累及口腔黏膜、生殖器和结膜。它已被记录为肺炎支原体感染的肺外表现之一。最近,有几例关于该综合征不完全表现的记录——没有典型皮疹,但有黏膜、结膜和生殖器受累。我们的病例表明,不完全性史蒂文斯-约翰逊综合征可能仅表现为口腔黏膜和结膜受累,而无皮肤或生殖器受累。由于其非典型表现,不应漏诊这一重要的临床诊断。如果确诊,史蒂文斯-约翰逊综合征的治疗仍然是支持性的,同时治疗潜在感染。