University of Genoa, Pediatria II, Istituto G Gaslini, Largo Gaslini 5, Genova 16147, Italy.
Ann Rheum Dis. 2012 Sep;71(9):1437-9. doi: 10.1136/annrheumdis-2012-201388. Epub 2012 Jun 7.
Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that encompasses all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. This heterogeneous group of chronic arthritides has been classified on clinical and laboratory grounds to try to identify homogeneous, mutually exclusives categories suitable for etiopathogenic studies . Recent advances have shown that while some JIA categories identify quite definite disease entities, others still include heterogeneous conditions. Some aspects of JIA classification and nomenclature need therefore to be reconsidered.
幼年特发性关节炎(JIA)不是一种疾病,而是一种排除性诊断,包括所有在 16 岁前发病、持续 6 周以上且病因不明的关节炎。为了尝试确定适合病因研究的同质、互斥的类别,对这组异质性慢性关节炎已根据临床和实验室标准进行了分类。最近的进展表明,虽然某些 JIA 类别确定了相当明确的疾病实体,但其他类别仍包括异质情况。因此,JIA 的分类和命名需要重新考虑。