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Rapidly progressive dementia due to leukocytoclastic vasculitis of the central nervous system.

作者信息

Pires Carolina, Foreid Henda, Barroso Cândida, Ferro José Manuel

机构信息

Department of Neurosciences, Hospital de Santa Maria, Lisbon, Portugal.

出版信息

BMJ Case Rep. 2011 Sep 28;2011:bcr0820114619. doi: 10.1136/bcr.08.2011.4619.

Abstract

A 70-year-old male was admitted with a 2-week progressive course of severe cognitive impairment, scoring three on the Mini Mental State Examination. MRI of the brain showed confluent hyperintense areas in T2/FLAIR in the periventricular and subcortical white matter, extending to right parietal cortex and basal ganglia. Intra-arterial angiography was unremarkable. A targeted stereotactic brain biopsy disclosed a leukocytoclastic vasculitis. The patient improved on steroids. Leukocytoclastic vasculitis adds to the spectrum of histopathologic subtypes of primary angiitis of the central nervous system.

摘要

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本文引用的文献

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Primary angiitis of the CNS.原发性中枢神经系统血管炎。
Lancet Neurol. 2011 Jun;10(6):561-72. doi: 10.1016/S1474-4422(11)70081-3.
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Vasculitis of the nervous system.神经系统血管炎
Curr Opin Neurol. 2004 Jun;17(3):317-36. doi: 10.1097/00019052-200406000-00014.

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