Bentin Thomas
Department of Cellular and Molecular Medicine; University of Copenhagen; Copenhagen, Denmark.
Artif DNA PNA XNA. 2012 Jan-Mar;3(1):3-4. doi: 10.4161/adna.19843.
A DNA capsule fitted with aptamer controlled target sensing has been "woven" using a 7308-base single-stranded DNA "thread" and 196 staple oligonucleotides. The capsule enables logic-gated molecular cargo delivery to targeted cell surfaces.
一种装有适配体控制的靶向传感功能的DNA胶囊,是利用一条7308个碱基的单链DNA“线”和196个短链寡核苷酸“编织”而成的。该胶囊能够实现逻辑门控的分子货物向靶向细胞表面的递送。