Samsygina G A, Vykhristiuk O F
Akush Ginekol (Sofiia). 1990;29(4):31-7.
An ontogenetic study of parameters of anticoagulative and fibrinolytic system in the blood and urine was carried out on 56 healthy newborn infants at the age of 3 to 28 days. The obtained data and the performed correlation analysis of the coagulative system showed that there was acceleration of fibrinolysis in blood on the background of increased antiplasmatic activity of the blood, RKFM and the concentration of fibrinogen B in blood plasma; the inhibitory activity of the urine, fibrinolytic activity of the urine and the content of PDF in urine were reduced in comparison with the same parameters in older infants. Maximal statistically significant correlation dependences were established during the first week of life of newborn infants. The obtained data could be used as controls in studying various pathological states, connected with changes in coagulative and anticoagulative systems.
对56名3至28天的健康新生儿进行了血液和尿液中抗凝和纤溶系统参数的个体发育研究。所获得的数据以及对凝血系统进行的相关性分析表明，在血液抗血浆活性、RKFM和血浆纤维蛋白原B浓度增加的背景下，血液中的纤溶加速；与较大婴儿的相同参数相比，尿液的抑制活性、尿液的纤溶活性和尿液中PDF的含量降低。在新生儿出生后的第一周建立了最大的统计学显著相关依赖性。所获得的数据可作为研究与凝血和抗凝系统变化相关的各种病理状态的对照。
