四名胆碱酯酶异常儿童对小剂量琥珀酰胆碱的反应——病例报告
Responses to small doses of suxamethonium in four children with abnormal cholinesterase--a case report.
作者信息
Brown T C, Meretoja O A, Bell B, Clare D
机构信息
Department of Anaesthesia, Royal Children's Hospital, Melbourne, Victoria, Australia.
出版信息
Anaesth Intensive Care. 1990 Nov;18(4):477-8. doi: 10.1177/0310057X9001800410.
PMID:2268012
Abstract
Four patients with genetic cholinesterase abnormalities were studied with electromyography after being given suxamethonium 0.1 mg/kg. An abnormal homozygous patient was paralysed for 17 minutes. The duration of response in heterozygous patients was 2-4 minutes, being shorter when cholinesterase activity levels were near normal.
摘要
对4例患有遗传性胆碱酯酶异常的患者给予0.1mg/kg琥珀酰胆碱后进行了肌电图研究。一名纯合子异常患者麻痹持续了17分钟。杂合子患者的反应持续时间为2 - 4分钟，当胆碱酯酶活性水平接近正常时持续时间更短。
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