Brown T C, Meretoja O A, Bell B, Clare D
Department of Anaesthesia, Royal Children's Hospital, Melbourne, Victoria, Australia.
Anaesth Intensive Care. 1990 Nov;18(4):477-8. doi: 10.1177/0310057X9001800410.
Four patients with genetic cholinesterase abnormalities were studied with electromyography after being given suxamethonium 0.1 mg/kg. An abnormal homozygous patient was paralysed for 17 minutes. The duration of response in heterozygous patients was 2-4 minutes, being shorter when cholinesterase activity levels were near normal.
对4例患有遗传性胆碱酯酶异常的患者给予0.1mg/kg琥珀酰胆碱后进行了肌电图研究。一名纯合子异常患者麻痹持续了17分钟。杂合子患者的反应持续时间为2 - 4分钟，当胆碱酯酶活性水平接近正常时持续时间更短。
