Zabobonin A I
Arkh Anat Gistol Embriol. 1990 Aug;99(8):64-9.
Longitudinal histological sections of lymphoid patches (LP) in the small intestine, stained after van Gieson and with hematoxylin--eosin, obtained from 105 corpses of persons at the age of 0 up to 90 years have been studied. The LP parenchyma is presented as accumulation of lymphoid nodules++ with a germinative center, or without it and diffuse lymphoid tissue. The lymphoid nodules++ situate both in the mucous membrane and in the submucous tela of the small intestine. The area of the LP components in the newborns is the greatest--84% from the whole area of the LP section. During the human life it decreases and by the old age it makes 47%. The lymphoid nodules++ area with the germinative center in the newborns makes 21% from the area of the LP section, in children from 1 to 3 years of age it increases up to 50%, then it gradually decreases and in the elderly age it makes only 3.8%. The diffuse lymphoid tissue in the LP composition is revealed in all age periods. Size of the lymphoid nodules++ patches, situating in the jejunum and ileum walls in the newborns is the same. In children at the age of 10 days--12 years the LP nodules++ in the ileum are larger than those in the sejunum. The size of the LP noduli increase up to the period of the second childhood then decreases. The height of the lymphoid noduli in persons of mature, elderly and old ages decreases twice in comparison with the children of 3-12 years of age.
对取自0至90岁105具尸体的小肠淋巴小结（LP）纵行组织切片进行了研究，这些切片经范吉森染色及苏木精-伊红染色。LP实质表现为有生发中心或无生发中心的淋巴小结++的聚集以及弥漫性淋巴组织。淋巴小结++位于小肠黏膜和黏膜下层。新生儿中LP各成分的面积最大，占LP切片总面积的84%。在人的一生中，该面积会减小，到老年时为47%。新生儿中有生发中心的淋巴小结++面积占LP切片面积的21%，1至3岁儿童中该比例增至50%，之后逐渐减小，到老年时仅为3.8%。LP组成中的弥漫性淋巴组织在所有年龄段均有发现。新生儿空肠和回肠壁中淋巴小结++斑块的大小相同。10天至12岁儿童中，回肠中的LP小结++比空肠中的大。LP小结的大小在第二个童年期之前会增大，之后减小。与3至12岁儿童相比，成年人、老年人和高龄老人的淋巴小结高度减小了一半。
