Sakimbaev E R
Arkh Anat Gistol Embriol. 1984 Aug;87(8):60-4.
The appendices from 121 corpses of persons died at the age 1 day--83 years have been studied. Increase in number and size of the lymph nodules in the appendix wall takes place up to 16 years of age. At the same age there is a certain increase in arrangement density of the lymph nodules from the base of the organ towards its apex. In childhood and adolescent age, in histological sections, the grouped lymph nodules are often arranged in 2-3 layers. The form of the nodules in transversal sections of the appendix in children and adolescents is round, oval and piriform, and at mature age and especially in aged and old persons, most of the nodules are flattened and elongated in transversal direction. The germinative centers are present in most of the lymph nodules in children up to 16 years of age, their number is less in mature persons and they are absent in the nodules in aged and old persons.
对121例年龄在1天至83岁死亡者的阑尾进行了研究。阑尾壁内淋巴小结的数量和大小在16岁前会增加。在同一年龄，从器官底部到顶端，淋巴小结的排列密度会有一定增加。在儿童和青少年时期，组织学切片中，成群的淋巴小结常呈2 - 3层排列。儿童和青少年阑尾横切面中的小结形态为圆形、椭圆形和梨形，而在成年人尤其是老年人中，大多数小结在横切面上是扁平且拉长的。16岁以下儿童的大多数淋巴小结中有生发中心，成年人中其数量较少，老年人的小结中则没有生发中心。
