Social and Behavioral Interventions Program, Dept of International Health, Johns Hopkins Bloomberg School of Public Health, USA.
Drug Alcohol Depend. 2012 Nov 1;126(1-2):195-9. doi: 10.1016/j.drugalcdep.2012.05.012. Epub 2012 Jun 6.
The joint effects of multiple social risk factors on substance use, such as parental divorce and parental history of depression, have rarely been studied in young adult offspring.
We examined the combined effects of parental divorce and parental history of depression on current cannabis use among a community sample of young adults in France. Parental divorce was ascertained as divorce or separation before 2009. Parental history of depression based on parental reports of depression (1989-2009) and offspring reports of parental lifetime history of depression. Current cannabis use was defined as use at least once in the preceding 12 months. Data were analyzed using multiple logistic regression models controlling for young adult and parental socio-demographic variables.
Approximately one fourth of youth (23%) reported consuming cannabis at least once in the past year. At the same time, 15% had parents who were divorced and 30% parents with a history of depression. The association between parental divorce and cannabis use in young adults was not statistically significant (adjusted OR: 1.50; 95% CI: 0.97-2.31). History of parental depression conferred a marginally statistically significant 42% higher odds of young adult cannabis use (adjusted OR: 1.42; 95% CI: 1.00-2.01). Young adults who experienced both parental history of divorce and depression were more than two times as likely to be current cannabis users compared to those who experienced neither of these (adjusted OR: 2.38; 95% CI: 1.26-4.48).
Our findings highlight the critical importance of considering familial context in understanding cannabis use in young adults.
父母离婚和父母抑郁史等多种社会风险因素对物质使用的联合影响在年轻成年子女中很少被研究。
我们研究了父母离婚和父母抑郁史对法国社区年轻成年人当前大麻使用的综合影响。父母离婚的定义为 2009 年之前的离婚或分居。父母抑郁史基于父母报告的抑郁（1989-2009 年）和子女报告的父母终身抑郁史。当前大麻使用定义为在过去 12 个月中至少使用过一次。数据分析采用多逻辑回归模型，控制年轻成年人和父母社会人口统计学变量。
大约四分之一的年轻人（23%）报告在过去一年中至少使用过一次大麻。同时，15%的年轻人父母离异，30%的年轻人父母有抑郁史。父母离婚与年轻人大麻使用之间的关联无统计学意义（调整后的 OR：1.50；95%CI：0.97-2.31）。父母抑郁史使年轻人大麻使用的可能性增加了 42%，但具有边缘统计学意义（调整后的 OR：1.42；95%CI：1.00-2.01）。经历过父母离异和抑郁史的年轻人成为当前大麻使用者的可能性是那些没有经历过这些情况的年轻人的两倍多（调整后的 OR：2.38；95%CI：1.26-4.48）。
我们的研究结果强调了在理解年轻人大麻使用时考虑家庭背景的重要性。
