Degrell I
Langenbecks Arch Chir. 1979 Aug;348(4):285-91. doi: 10.1007/BF01317615.
8 cases of Paget's disease of the nipple were diagnosed by means of cytological examination: in 6 patients by exfoliative, in 2 patients by aspiration biopsy cytology. The diagnoses were verified histologically. Early exfoliative cytology is recommended for early diagnosis in all cases of Paget's mamillae. This method is quick, safe, easily to be carried into effect and to apply repeatedly; but, if the process is suspected of malignancy, a trial-excision has to be carried out. A well-trained cytologist rarely needs the latter. This simple method will reduce the development of advanced Paget's disease.
通过细胞学检查诊断出8例乳头佩吉特病:6例通过脱落细胞学检查,2例通过针吸活检细胞学检查。诊断经组织学证实。对于所有乳头佩吉特病病例,建议早期进行脱落细胞学检查以实现早期诊断。该方法快速、安全、易于实施且可重复应用;但是,如果怀疑该病变为恶性,则必须进行试验性切除。训练有素的细胞学家很少需要后者。这种简单的方法将减少晚期佩吉特病的发生。