Mycology Section, Department of Dermatology, Dr. Manuel Gea Gonzalez General Hospital, Calzada de Tlalpan 4800, Colonia Sección XVI, Mexico, DF Mexico.
Clin Dermatol. 2012 Jul-Aug;30(4):403-8. doi: 10.1016/j.clindermatol.2011.09.011.
Chromoblastomycosis is a chronic, subcutaneous mycosis, characterized by verrucous nodular lesions, usually involving the legs and mainly caused by Fonsecaea, Phialophora, and Cladophialophora spp. The characteristic finding on direct examination or biopsy specimen is the presence of fumagoid cells or Medlar bodies. Chromoblastomycosis can be refractory to medical treatment. Therapeutic options include oral itraconazole, terbinafine, or 5-fluocytosine, alone or combined with surgery or cryosurgery.
着色芽生菌病是一种慢性皮下真菌病，特征为疣状结节病变，通常累及下肢，主要由帚霉属、瓶霉属和枝孢霉属引起。直接检查或活检标本的特征性发现是存在烟曲霉菌细胞或梅迪尔体。着色芽生菌病对药物治疗有抗性。治疗选择包括单独使用或与手术或冷冻手术联合使用口服伊曲康唑、特比萘芬或 5-氟胞嘧啶。
