Faculty of Medicine, Nilton Liins University, Av. Professor Nilton Lins 3259, Parque das Laranjeiras, Manaus, Amazonas, Brazil.
Clin Dermatol. 2012 Jul-Aug;30(4):420-4. doi: 10.1016/j.clindermatol.2011.09.014.
Lobomycosis is a rare chronic fungal infection of the subcutaneous tissue found in South America, mainly in Brazil. It is caused by Lacazia loboi. Its clinical manifestations are dermal nodules, either lenticular or in plaques, and keloidlike lesions that can resemble nodular leprosy or leishmaniasis, other subcutaneous mycoses (sporotrychosis, chromomycosis, paracoccidioidomycosis), keloids, and malignant tumors. Diagnosis is made by the histopathological findings of the fungus. For treatment, surgical removal of the lesions, followed by itraconazole and clofazimine for disseminated lesions, has been used with variable results.
利什曼原虫病是一种罕见的慢性真菌性皮下组织感染，主要见于南美洲，特别是巴西。它是由拉沙热原虫引起的。其临床表现为皮肤结节，呈透镜状或斑块状，以及类似瘢痕疙瘩的病变，这些病变可能类似于结节性麻风或利什曼病、其他皮下真菌病（孢子丝菌病、着色真菌病、副球孢子菌病）、瘢痕疙瘩和恶性肿瘤。诊断是通过真菌的组织病理学发现。对于治疗，手术切除病变，然后用伊曲康唑和氯法齐明治疗播散性病变，已取得不同的结果。
