Service of Dermatology, Department of Dermatopathology, Universidade Federal do Pará, Belém, PA, Brazil.
Service of Dermatology, Universidade Federal do Pará, Belém, PA, Brazil.
An Bras Dermatol. 2022 Jan-Feb;97(1):93-95. doi: 10.1016/j.abd.2021.08.001. Epub 2021 Nov 23.
Jorge Lobo's disease (JLD) is a chronic, granulomatous fungal infection caused by the traumatic implantation of the fungus Lacazia loboi in the cutaneous and subcutaneous tissues, with the presence of isolated nodular and coalescent keloidal lesions. Malignant degeneration is rare. This case report describes a 64-year-old male patient with JLD for 30-years who showed a change in the aspect of a lesion in the left lower limb. Histopathological examination confirmed the progression to well-differentiated squamous cell carcinoma (SSC). JLD is highly prevalent in tropical and subtropical regions, requiring monitoring concerning the transformation into SSC in long-term lesions.
若泽-洛博病（JLD）是一种慢性、肉芽肿性真菌感染，由创伤性植入拉卡齐亚·洛博菌引起，发生于皮肤和皮下组织，表现为孤立性结节状和融合性瘢痕疙瘩样病变。恶性转化罕见。本病例报告描述了一名 64 岁男性患者，患有 JLD30 年，左下肢病变出现变化。组织病理学检查证实进展为分化良好的鳞状细胞癌（SSC）。JLD 在热带和亚热带地区高发，需要对长期病变中向 SSC 的转化进行监测。
