Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA.
Clin Perinatol. 2012 Jun;39(2):387-401. doi: 10.1016/j.clp.2012.04.011. Epub 2012 May 18.
Necrotizing enterocolitis (NEC) is the most common acquired gastrointestinal disease of premature neonates and is a serious cause of morbidity and mortality. NEC is one of the leading causes of death in neonatal intensive care units. Surgical treatment is necessary in patients whose disease progresses despite medical therapy. Surgical options include peritoneal drainage and laparotomy, with studies showing no difference in outcome related to approach. Survivors, particularly those requiring surgery, face serious sequelae.
新生儿坏死性小肠结肠炎(NEC)是早产儿最常见的获得性胃肠道疾病,也是发病率和死亡率的严重原因。NEC 是新生儿重症监护病房死亡的主要原因之一。尽管进行了药物治疗,但病情仍在进展的患者需要进行手术治疗。手术选择包括腹腔引流和剖腹术,研究表明手术方式与结果无关。幸存者,特别是那些需要手术的患者,面临严重的后遗症。