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坏死性小肠结肠炎。

Necrotizing enterocolitis.

机构信息

Department of Surgery, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA.

出版信息

Clin Perinatol. 2012 Jun;39(2):387-401. doi: 10.1016/j.clp.2012.04.011. Epub 2012 May 18.

DOI:10.1016/j.clp.2012.04.011
PMID:22682387
Abstract

Necrotizing enterocolitis (NEC) is the most common acquired gastrointestinal disease of premature neonates and is a serious cause of morbidity and mortality. NEC is one of the leading causes of death in neonatal intensive care units. Surgical treatment is necessary in patients whose disease progresses despite medical therapy. Surgical options include peritoneal drainage and laparotomy, with studies showing no difference in outcome related to approach. Survivors, particularly those requiring surgery, face serious sequelae.

摘要

新生儿坏死性小肠结肠炎(NEC)是早产儿最常见的获得性胃肠道疾病,也是发病率和死亡率的严重原因。NEC 是新生儿重症监护病房死亡的主要原因之一。尽管进行了药物治疗,但病情仍在进展的患者需要进行手术治疗。手术选择包括腹腔引流和剖腹术,研究表明手术方式与结果无关。幸存者,特别是那些需要手术的患者,面临严重的后遗症。

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Necrotizing enterocolitis.坏死性小肠结肠炎。
Clin Perinatol. 2012 Jun;39(2):387-401. doi: 10.1016/j.clp.2012.04.011. Epub 2012 May 18.
2
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Evidence vs experience in the surgical management of necrotizing enterocolitis and focal intestinal perforation.坏死性小肠结肠炎和局限性肠穿孔外科治疗中的证据与经验
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Outcome of perforated necrotizing enterocolitis in the very low-birth weight neonate may be independent of the type of surgical treatment.极低出生体重儿坏死性小肠结肠炎穿孔的预后可能与手术治疗方式无关。
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The use of the score for neonatal acute physiology-perinatal extension (SNAPPE II) in perforated necrotizing enterocolitis: could it guide therapy in newborns less than 1500 g?新生儿急性生理学-围产期扩展评分(SNAPPE II)在穿孔性坏死性小肠结肠炎中的应用:它能否指导体重小于1500克新生儿的治疗?
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Peritoneal drainage as definitive treatment for neonates with isolated intestinal perforation.腹腔引流作为孤立性肠穿孔新生儿的确定性治疗方法。
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