Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.
Friedrich-Loeffler-Institute, Naumburger Str. 96a, 07743 Jena, Germany.
J Med Microbiol. 2012 Sep;61(Pt 9):1335-1337. doi: 10.1099/jmm.0.038612-0. Epub 2012 Jun 8.
Brucellosis is a regionally emerging infectious disease in Mediterranean countries with an increasing number of human cases and high morbidity rates. Here, we describe a case of severe B. melitensis biotype 3 infection in an immigrant who had contact with ruminants during a short-term stay in Bosnia before he returned to Germany. The patient developed thoracic spondylodiscitis accompanied by a large epidural empyema and neurological deficits. The isolated strain was characterized and compared to other strains from the Mediterranean region by multiple locus variable number of tandem repeat analysis, showing minor differences between emerging strains from neighbouring geographical areas.
布鲁氏菌病是在地中海国家出现的一种区域性传染病，人类病例不断增加，发病率较高。在这里，我们描述了一名移民的病例，他在返回德国之前在波斯尼亚短期逗留期间接触过反刍动物，患有严重的 B. melitensis 生物型 3 感染。患者出现胸椎间盘炎，伴有大的硬膜外脓肿和神经功能缺损。通过多位点可变串联重复分析对分离株进行了特征描述和与来自地中海地区的其他菌株进行了比较，结果表明来自相邻地理区域的新兴菌株之间存在微小差异。
