Department of Computer Science, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi 110025, India.
Genomics. 2012 Aug;100(2):65-71. doi: 10.1016/j.ygeno.2012.05.014. Epub 2012 Jun 5.
The aim of this paper is to provide an introduction to the rapidly developing field of genetic programming (GP). Particular emphasis is placed on the application of GP to genomics. First, the basic methodology of GP is introduced. This is followed by a review of applications in the areas of gene network inference, gene expression data analysis, SNP analysis, epistasis analysis and gene annotation. Finally this paper concluded by suggesting potential avenues of possible future research on genetic programming, opportunities to extend the technique, and areas for possible practical applications.
本文旨在对快速发展的遗传编程(GP)领域进行介绍。特别强调了 GP 在基因组学中的应用。首先,介绍了 GP 的基本方法。接着,回顾了在基因网络推断、基因表达数据分析、SNP 分析、上位性分析和基因注释等领域的应用。最后,本文通过提出遗传编程可能的未来研究方向、扩展技术的机会以及可能的实际应用领域,对遗传编程的未来进行了展望。