Hu Ying, Yu Chuanhua, Chen Banghua, Wang Lei
Department of Epidemiology and Biostatistics, School of Public Health of Wuhan University, Wuhan, 430071, China.
Wuhan University Global Health Institute, Wuhan, 430071, China.
J Huazhong Univ Sci Technolog Med Sci. 2012 Jun;32(3):428-433. doi: 10.1007/s11596-012-0074-y. Epub 2012 Jun 9.
This study examined the change of reported incidence rate for viral hepatitis in Hubei province, China, between 2004 to 2010 to provide scientific evidence for viral hepatitis control. Reported viral hepatitis infection cases were queried from Centre for Disease Control of Hubei Province, China. The incidence of viral hepatitis A decreased steadily across the study period. Viral hepatitis B composed 85% of the viral hepatitis cases. When reported incidence rates for chronic hepatitis B increased, the rates of acute and unclassified cases dropped from 2005 to 2010. The reported viral hepatitis B incidence rate for males was around 1.5-2 times higher than for females. The average annual percentage change of reported viral hepatitis B incidence rates was 4%. The same index for viral hepatitis C was 28%. The reported viral hepatitis B incidence rate of people under 20 years old declined over the period. This decrease was mainly attributed to the recent implementation of vaccination plan. Reported incidence rate of viral hepatitis E also rose in those years. Having a better understanding on reported incidence rates of the present surveillance system is important for developing strategies for further prevention of viral hepatitis. In addition, the data showed that a surveillance system that differentiates new and former infected cases will be more effective in providing evidence for disease control.
本研究调查了2004年至2010年间中国湖北省报告的病毒性肝炎发病率变化情况，为病毒性肝炎防控提供科学依据。从中国湖北省疾病预防控制中心查询报告的病毒性肝炎感染病例。在整个研究期间，甲型病毒性肝炎的发病率稳步下降。乙型病毒性肝炎占病毒性肝炎病例的85%。2005年至2010年，慢性乙型肝炎报告发病率上升时，急性和未分类病例的发病率下降。男性报告的乙型病毒性肝炎发病率约为女性的1.5至2倍。报告的乙型病毒性肝炎发病率的年均变化率为4%。丙型病毒性肝炎的同一指标为28%。20岁以下人群报告的乙型病毒性肝炎发病率在此期间有所下降。这种下降主要归因于近期实施的疫苗接种计划。那些年戊型病毒性肝炎的报告发病率也有所上升。更好地了解当前监测系统的报告发病率对于制定进一步预防病毒性肝炎的策略很重要。此外，数据表明，区分新感染病例和既往感染病例的监测系统在为疾病防控提供证据方面将更有效。
