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急性心脑血管意外和中风溶栓治疗后自发性冠状动脉血栓形成:病例研究。

Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: a case study.

机构信息

Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, The Lexington VA Medical Center, 900 S. Limestone Street, 326 CTW Building, Lexington, KY 40536-0200, USA.

出版信息

J Thromb Thrombolysis. 2012 Nov;34(4):548-51. doi: 10.1007/s11239-012-0754-2.

Abstract

Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

摘要

心脏并发症是中风或急性脑血管意外(CVA)后的常见并发症;然而,其中许多并发症是无症状的,不会引起不良的心脏影响。有症状的事件(如 CVA 后急性心肌梗死)很少发生,通常是潜在的心脏栓子来源的结果,如左心室血栓。我们报告了一例急性 CVA 溶栓治疗后自发性冠状动脉血栓形成的病例,并讨论了潜在的全身性促血栓形成状态可能使个体易发生不同血管床的血栓形成的意义。

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本文引用的文献

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Platelet activation and its patient-specific consequences.
Thromb Res. 2008;122(4):435-41. doi: 10.1016/j.thromres.2007.08.023. Epub 2007 Oct 22.

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