University of Texas Medical Branch, Galveston, TX, USA.
Aesthetic Plast Surg. 2012 Oct;36(5):1160-3. doi: 10.1007/s00266-012-9929-7. Epub 2012 Jun 9.
Reported herein are three cases of spontaneous bradycardia progressing to asystole during routine breast augmentation in healthy, adult female patients with a history of endurance training and resting bradycardia (heart rate <60 beats per minute). The incidence of this phenomenon is minimally reported and virtually unexplained in literature. Our goal is to alert the plastic surgery community of the possibility of these events occurring without warning in athletic patients, attempt to explain these findings, and provide a plan of action to minimize morbidity and mortality in these patients. The most severe case was that of a 38-year-old female who became severely bradycardic progressing to asystole during routine breast augmentation. She had no history of any medical problems, but did have a resting heart rate of <60. Glycopyrrolate, an antimuscarinic agent, was given and chest compressions started. After 10-20 s of chest compressions the patient's normal sinus rhythm resumed. Two other cases are also reported, although these patients responded to antimuscarinic agents without requiring chest compressions. Both were endurance athletes with a resting heart rate of <60. Bradycardia caused by a vagal response during surgery is not uncommon and routinely treated successfully with administration of atropine-like agents. Bradycardia progressing to frank asystole is rare and has not been reported in young, otherwise healthy, aesthetic surgery patients. This report should serve to alert the plastic surgeon to the possibility of this situation occurring and how to treat it successfully, especially in the outpatient or office-based surgery setting. Level of Evidence V This journal requires that authors assign a level of evidence to each article.
本文报告了三例在健康成年女性中进行常规乳房增大手术时,由于既往有耐力训练和静息心动过缓(心率<60 次/分钟),出现自发性心动过缓进展为心搏停止的病例。这种现象的发生率在文献中鲜有报道,几乎无法解释。我们的目标是提醒整形外科学界注意这种情况可能在运动患者中毫无征兆地发生,尝试解释这些发现,并提供行动计划,以最大限度地降低这些患者的发病率和死亡率。最严重的病例是一名 38 岁女性,在常规乳房增大手术中出现严重心动过缓,进展为心搏停止。她没有任何医疗问题史,但静息心率<60。给予了抗毒蕈碱药物格隆溴铵,开始进行胸外按压。在进行 10-20 秒的胸外按压后,患者恢复正常窦性心律。另外还报告了两例病例,尽管这些患者无需进行胸外按压,就对抗毒蕈碱药物有反应。这两名患者都是耐力运动员,静息心率<60。手术期间由于迷走神经反应引起的心动过缓并不罕见,常规使用类似阿托品的药物治疗即可成功。心动过缓进展为完全心搏停止较为罕见,尚未在年轻、健康的美容手术患者中报道过。本报告应提醒整形外科医生注意这种情况发生的可能性以及如何成功治疗,尤其是在门诊或办公室手术环境中。证据等级 V 本杂志要求作者为每篇文章分配证据等级。