Vijayakrishnan Rajakrishnan, Rapose Alwyn
Department of Cardiovascular Medicine, Geisinger Health System, Danville, Pennsylvania, USA.
BMJ Case Rep. 2012 Jun 8;2012:bcr0220125855. doi: 10.1136/bcr-02-2012-5855.
Most enterococcal endocarditis is caused by Enterococcus faecalis and Enterococcus faecium. Enterococcus durans is a rare member of non-faecalis, non-faecium enterococcal species and is found in the intestines of animals. E durans endocarditis is a very rare infection-only two cases of endocarditis in humans have been reported in the literature-and usually associated with good outcomes when treated with appropriate antibiotics. We report the first case of fatal E durans endocarditis. This patient had end-stage liver disease with associated compromised immune status that likely contributed to the progression of disease in spite of appropriate antibiotic coverage and clearance of bacteraemia.
大多数肠球菌性心内膜炎由粪肠球菌和屎肠球菌引起。耐久肠球菌是粪肠球菌和屎肠球菌以外的肠球菌属中的罕见成员,存在于动物肠道中。耐久肠球菌性心内膜炎是一种非常罕见的感染——文献中仅报道了两例人类心内膜炎病例——通常在使用适当抗生素治疗时预后良好。我们报告了首例致命的耐久肠球菌性心内膜炎病例。该患者患有终末期肝病且免疫状态受损,尽管给予了适当的抗生素治疗并清除了菌血症,但这可能仍促使了疾病的进展。