人冠状动脉和人隐静脉对5-羟色胺的收缩反应。
Contractions to 5-hydroxytryptamine in human coronary artery and human saphenous vein.
作者信息
Borton M, Neligan M, Wood F, Dervan P, Goggins K, Docherty J R
机构信息
Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland.
出版信息
Br J Clin Pharmacol. 1990;30 Suppl 1(Suppl 1):107S-108S. doi: 10.1111/j.1365-2125.1990.tb05476.x.
Abstract
Isometric contractions were obtained to 5-hydroxytryptamine receptor agonists in human saphenous vein and human coronary artery. Based on the interaction with the 5-HT2 receptor antagonist ketanserin, both 5-HT1 and 5-HT2 receptors are involved in contractions of human saphenous vein, but the predominant subtype involved in contractions of human coronary artery is the 5-HT1 receptor.
摘要
在人隐静脉和人冠状动脉中获得了对5-羟色胺受体激动剂的等长收缩。基于与5-HT2受体拮抗剂酮色林的相互作用，5-HT1和5-HT2受体均参与人隐静脉的收缩，但参与人冠状动脉收缩的主要亚型是5-HT1受体。
相似文献
1
Contractions to 5-hydroxytryptamine in human coronary artery and human saphenous vein.人冠状动脉和人隐静脉对5-羟色胺的收缩反应。
Br J Clin Pharmacol. 1990;30 Suppl 1(Suppl 1):107S-108S. doi: 10.1111/j.1365-2125.1990.tb05476.x.
2
Studies on the mechanism of 5-HT1 receptor-induced smooth muscle contraction in dog saphenous vein.犬隐静脉中5-羟色胺1型受体诱导平滑肌收缩机制的研究。
Br J Pharmacol. 1992 Mar;105(3):603-8. doi: 10.1111/j.1476-5381.1992.tb09026.x.
3
GR43175, a selective agonist for the 5-HT1-like receptor in dog isolated saphenous vein.GR43175，一种犬离体隐静脉中5-HT1样受体的选择性激动剂。
Br J Pharmacol. 1988 Aug;94(4):1123-32. doi: 10.1111/j.1476-5381.1988.tb11630.x.
4
A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists.介导兔主动脉和犬隐静脉收缩的5-羟色胺受体比较：使用选择性激动剂和拮抗剂获得不同受体类型的证据。
Br J Pharmacol. 1985 Nov;86(3):697-704. doi: 10.1111/j.1476-5381.1985.tb08948.x.
5
Serotonin-induced contraction in porcine coronary artery: use of ergolines to support vascular 5-hydroxytryptamine2-receptor heterogeneity.血清素诱导的猪冠状动脉收缩：使用麦角灵类药物来支持血管5-羟色胺2受体的异质性。
J Pharmacol Exp Ther. 1993 Jan;264(1):193-200.
6
The actions of 5-hydroxytryptamine receptor agonists and antagonists at pre- and postjunctional level on the canine saphenous vein.5-羟色胺受体激动剂和拮抗剂对犬隐静脉节前和节后水平的作用。
Naunyn Schmiedebergs Arch Pharmacol. 1988 Dec;338(6):616-22. doi: 10.1007/BF00165625.
7
An examination of 5-hydroxytryptamine receptors in human saphenous vein.人隐静脉中5-羟色胺受体的检测
Br J Pharmacol. 1986 Sep;89(1):77-81. doi: 10.1111/j.1476-5381.1986.tb11122.x.
8
5-Hydroxytryptamine receptor profile in healthy and diseased human epicardial coronary arteries.健康和患病人类心外膜冠状动脉中的5-羟色胺受体分布
Cardiovasc Res. 1990 Nov;24(11):932-7. doi: 10.1093/cvr/24.11.932.
9
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.血清素诱导的犬冠状动脉和隐静脉收缩：一种类5-HT1D受体的作用。
Life Sci. 1994;54(22):1671-80. doi: 10.1016/0024-3205(94)00607-5.
10
Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.5-羟色胺（5-HT）诱导的去内皮兔心外膜冠状动脉收缩中5-HT（1B/1D）和5-HT2A受体的作用。
Br J Pharmacol. 1997 Nov;122(5):875-84. doi: 10.1038/sj.bjp.0701470.
引用本文的文献
1
Serotonin and blood pressure regulation.血清素与血压调节。
Pharmacol Rev. 2012 Apr;64(2):359-88. doi: 10.1124/pr.111.004697. Epub 2012 Mar 8.
2
Clinical pharmacology, physiology and pathophysiology of superficial veins--2.浅静脉的临床药理学、生理学及病理生理学——2.
Br J Clin Pharmacol. 1994 Oct;38(4):289-305. doi: 10.1111/j.1365-2125.1994.tb04357.x.
3
Cloning and functional characterization of the rat stomach fundus serotonin receptor.大鼠胃底5-羟色胺受体的克隆及功能特性研究
EMBO J. 1992 Sep;11(9):3481-7. doi: 10.1002/j.1460-2075.1992.tb05427.x.
本文引用的文献
1
Vascular serotonin receptors. Correlation with 5-HT1 and 5-HT2 binding sites.血管血清素受体。与5-HT1和5-HT2结合位点的相关性。
Biochem Pharmacol. 1984 Aug 1;33(15):2349-53. doi: 10.1016/0006-2952(84)90704-4.
2
An examination of 5-hydroxytryptamine receptors in human saphenous vein.人隐静脉中5-羟色胺受体的检测
Br J Pharmacol. 1986 Sep;89(1):77-81. doi: 10.1111/j.1476-5381.1986.tb11122.x.
3
Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery.犬冠状动脉平滑肌和内皮细胞上5-羟色胺能受体亚型的比较。
J Pharmacol Exp Ther. 1988 Jan;244(1):1-10.
4
A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists.介导兔主动脉和犬隐静脉收缩的5-羟色胺受体比较：使用选择性激动剂和拮抗剂获得不同受体类型的证据。
Br J Pharmacol. 1985 Nov;86(3):697-704. doi: 10.1111/j.1476-5381.1985.tb08948.x.
5
5-Hydroxytryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation.
Eur J Pharmacol. 1989 Feb 14;161(1):91-4. doi: 10.1016/0014-2999(89)90184-2.
Zotero 插件