家族性原发性血小板增多症。

Familial essential thrombocythemia.

作者信息

Fernandez-Robles E, Vermylen C, Martiat P, Ninane J, Cornu G

机构信息

Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, Brussels, Belgium.

出版信息

Pediatr Hematol Oncol. 1990;7(4):373-6. doi: 10.3109/08880019009033414.

DOI:10.3109/08880019009033414

PMID:2268537

Abstract

We report three siblings (2 F, 1 M) aged 9, 12, and 15 years with a thrombocytosis, above 650 X 10(9)/l for at least 18 months and a leukocyte alkaline phosphatase score below 37. The diagnosis of essential thrombocythemia was based upon the exclusion of a reactive thrombocytosis or another myeloproliferative disease. Cytogenetic examination of marrow cells was normal.

摘要

我们报告了三名兄弟姐妹（2名女性，1名男性），年龄分别为9岁、12岁和15岁，患有血小板增多症，血小板计数至少18个月高于650×10⁹/L，白细胞碱性磷酸酶评分低于37。原发性血小板增多症的诊断基于排除反应性血小板增多症或其他骨髓增殖性疾病。骨髓细胞的细胞遗传学检查正常。