Foulkes Rhiannon, Hoare David, Somasekar Krishnamurthy
General Surgery Department, Nevill Hall Hospital, Abergavenny, UK.
BMJ Case Rep. 2011 Aug 4;2011:bcr0620114346. doi: 10.1136/bcr.06.2011.4346.
The authors present a case of necrotising fasciitis of the peristomal area, in a patient who had undergone a previous ileostomy for ulcerative colitis. This was associated with neutropaenia, secondary to carbimazole, which had been commenced a few weeks previously for thyrotoxicosis. The authors therefore, stress the importance of monitoring patients closely for possible side effects and complications, while they are on immunosuppressive medication.
作者报告了一例造口周围坏死性筋膜炎病例,患者曾因溃疡性结肠炎接受回肠造口术。这与中性粒细胞减少有关,中性粒细胞减少继发于卡比马唑,卡比马唑几周前因甲状腺毒症开始使用。因此,作者强调在患者使用免疫抑制药物时密切监测其可能出现的副作用和并发症的重要性。