Kawsar Hameem I, Spiro Timothy P, Daw Hamed A
Department of Internal Medicine, Fairview Hospital, Cleveland, Ohio, USA.
BMJ Case Rep. 2011 Aug 11;2011:bcr0420114060. doi: 10.1136/bcr.04.2011.4060.
A 47-year-old female presented with a 2-week history of painless haematuria. Urine dipstick showed moderate leucocytes. Blood and urine cultures were negative and cytology was negative for malignant cells. Flexible cystoscopy was negative for any bladder pathology. An ultrasonogram of the abdomen showed a mass in the left kidney. CT showed a mass-like lesion within the left kidney suspicious for renal carcinoma, and cavitary lesions in both lungs. Biopsy of the lung showed clusters of atypical cells suspicious for squamous cell carcinoma (SCC), and left kidney lesion showed malignant cells derived from SCC. A whole body positron emission tomography/CT showed lesions in the lungs, left kidney and skeleton. Complete clinical examination, laboratory and imaging studies did not reveal any site of primary tumour in any part of the body. Haematuria is a very unusual initial presentation of metastatic tumour to kidney.
一名47岁女性,有2周无痛性血尿病史。尿试纸检测显示中度白细胞。血培养和尿培养均为阴性,细胞学检查未发现恶性细胞。软性膀胱镜检查未发现任何膀胱病变。腹部超声显示左肾有一肿块。CT显示左肾内有一肿块样病变,怀疑为肾癌,双肺有空洞性病变。肺部活检显示有可疑鳞状细胞癌(SCC)的非典型细胞簇,左肾病变显示有源自SCC的恶性细胞。全身正电子发射断层扫描/CT显示肺部、左肾和骨骼有病变。完整的临床检查、实验室检查和影像学检查未发现身体任何部位有原发性肿瘤。血尿是转移性肿瘤累及肾脏非常罕见的首发表现。