Piudo Luciana, Monteverde Martin J, Walker R Susan, Douglass Richard J
Depto. Fauna Terrestre, Centro de Ecología Aplicada del Neuquén.
Rev Chilena Infectol. 2012 Apr;29(2):200-6. doi: 10.4067/S0716-10182012000200013.
Oligoryzomys longicaudatus is the main reservoir of Andes virus (AND), which causes hantavirus pulmonary syndrome in Patagonia. The factors associated with the presence of antibodies against AND in this species are unknown. This study used a logistic regression model to analyze which characteristics of O. longicaudatus, captured in northern Argentinean Patagonia, led to an increased probability of an animal having antibodies against AND and to relate these characteristics to possible mechanisms of transmission of the virus within the population. Sex, age, body mass, and wounds were important predictors regarding the presence of antibodies against AND within O. longicaudatus populations. The probability of a wounded male O. longicaudatus adult having AND antibodies increased in parallel with the body mass. The probability of having antibodies was more than 80% in individuals with body masses above 44 gram. However, the possible transmission mechanism of AND within O. longicaudatus population is still uncertain and further studies involving a larger number of individuals and prolonged monitoring including the process of seroconversion are needed.
长尾稻鼠是安第斯病毒(AND)的主要宿主,该病毒在巴塔哥尼亚引发汉坦病毒肺综合征。与该物种中抗AND抗体存在相关的因素尚不清楚。本研究使用逻辑回归模型分析在阿根廷巴塔哥尼亚北部捕获的长尾稻鼠的哪些特征导致动物产生抗AND抗体的概率增加,并将这些特征与病毒在种群内可能的传播机制联系起来。性别、年龄、体重和伤口是长尾稻鼠种群中抗AND抗体存在的重要预测因素。成年受伤雄性长尾稻鼠产生AND抗体的概率与体重平行增加。体重超过44克的个体产生抗体的概率超过80%。然而,AND在长尾稻鼠种群内可能的传播机制仍不确定,需要进一步开展涉及更多个体的研究以及包括血清转化过程在内的长期监测。