Qiu W S, Chen K J, Li C S
Xiyuan Hospital, China Academy of TCM, Beijing.
Zhong Xi Yi Jie He Za Zhi. 1990 Sep;10(9):532-4, 516.
A total of 51 cases with hyperlipidemia, who were defined deficiency symptom-complex complicated by symptoms of excessiveness in TCM were studied clinically. The patients were divided into two groups at random. One group was treated with Xiaobu Jianfei Pian (XJP) as treated group, another with Fangfeng Tongsheng San as a control. It was found that XJP was able to lower total serum cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and apolipoprotein (apo) B significantly (P less than 0.001, 0.001, 0.001) while it had markedly improved clinical symptoms. It was also observed that XJP had good effects on the ratios of apoA1/B and TC/HDL-C, and was able to reduce body weight index. All of these were better than those of the control group statistically. These evidences indicate that XJP possesses clinical therapeutic effects on both lipid-lowering and lipid-adjusting, which suggest that XJP may be an effective anti-hyperlipidemia medicine.
共对51例中医辨证为虚证兼实证的高脂血症患者进行了临床研究。将患者随机分为两组。一组服用消补减肥片(XJP)作为治疗组,另一组服用防风通圣散作为对照组。结果发现,XJP能显著降低血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和载脂蛋白(apo)B(P均小于0.001),同时明显改善临床症状。还观察到,XJP对apoA1/B和TC/HDL-C比值有良好影响,并能降低体重指数。所有这些在统计学上均优于对照组。这些证据表明,XJP具有降脂和调脂的临床治疗作用,提示XJP可能是一种有效的抗高脂血症药物。