• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

N-甲基-D-天冬氨酸受体脑炎——临床谱的扩展

NMDA receptor encephalitis--expanding the clinical spectrum.

作者信息

Nath Uma, Warren Naomi Margaret, Ali Husam

机构信息

Neurology Department, Sunderland Royal Hospital, Sunderland, Tyne and Wear, UK.

出版信息

BMJ Case Rep. 2011 Jul 28;2011:bcr1220103579. doi: 10.1136/bcr.12.2010.3579.

DOI:10.1136/bcr.12.2010.3579
PMID:22689858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3149505/
Abstract

A young woman presented with memory problems of subacute onset. Imaging was normal. She was admitted with severe complex partial status epilepticus requiring intensive care support and ventilation. Fits proved difficult to control requiring high dose anticonvulsants. She developed a profound amnesic syndrome. A clinical diagnosis of autoimmune encephalitis was considered and she was treated with intravenous steroids with an excellent cognitive outcome. She continues to have occasional seizures.

摘要

一名年轻女性出现亚急性起病的记忆问题。影像学检查正常。她因严重的复杂部分性癫痫持续状态入院,需要重症监护支持和通气。癫痫发作难以控制,需要大剂量抗惊厥药物。她发展为严重的遗忘综合征。考虑自身免疫性脑炎的临床诊断,她接受了静脉注射类固醇治疗,认知结果良好。她仍偶尔有癫痫发作。

相似文献

1
NMDA receptor encephalitis--expanding the clinical spectrum.N-甲基-D-天冬氨酸受体脑炎——临床谱的扩展
BMJ Case Rep. 2011 Jul 28;2011:bcr1220103579. doi: 10.1136/bcr.12.2010.3579.
2
[Acute encephalitis with refractory partial status epilepticus treated with early immunotherapies including plasma exchange: a case report].[采用包括血浆置换在内的早期免疫疗法治疗的伴有难治性部分性癫痫持续状态的急性脑炎:一例报告]
Rinsho Shinkeigaku. 2014;54(9):715-20. doi: 10.5692/clinicalneurol.54.715.
3
Antiepileptic treatment for anti-NMDA receptor encephalitis: the need for video-EEG monitoring.抗 N-甲基-D-天冬氨酸受体脑炎的抗癫痫治疗:视频脑电图监测的必要性。
Epileptic Disord. 2013 Jun;15(2):166-70. doi: 10.1684/epd.2013.0566.
4
An unusual case of refractory status epilepticus in a young lady: anti-NMDA receptor encephalitis.一位年轻女士中抗 NMDA 受体脑炎致难治性癫痫持续状态的不寻常病例
Clin Med (Lond). 2017 Oct;17(5):436-438. doi: 10.7861/clinmedicine.17-5-436.
5
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.抗 N-甲基-D-天冬氨酸受体脑炎患者的重症监护。
Am J Respir Crit Care Med. 2017 Feb 15;195(4):491-499. doi: 10.1164/rccm.201603-0507OC.
6
Acute psychiatric illness in a young woman: an unusual form of encephalitis.一名年轻女性的急性精神疾病:一种不寻常的脑炎形式。
Med J Aust. 2009 Sep 7;191(5):284-6. doi: 10.5694/j.1326-5377.2009.tb02787.x.
7
An Unusual Cause of Frequent, Sudden, Transient, Unexplained Falls and New-Onset Status Epilepticus: Case Report and Mini-Review.
Clin Pediatr (Phila). 2018 Feb;57(2):173-179. doi: 10.1177/0009922817698805. Epub 2017 Apr 19.
8
Case report: meningitis as a presenting feature of anti-NMDA receptor encephalitis.病例报告:以脑膜炎为表现的抗 NMDA 受体脑炎。
BMC Infect Dis. 2020 Jan 7;20(1):21. doi: 10.1186/s12879-020-4761-1.
9
Anti-NMDA-R encephalitis: Should we consider extreme delta brush as electrical status epilepticus?抗N-甲基-D-天冬氨酸受体(NMDA-R)脑炎:我们是否应将极端δ刷视为癫痫持续状态?
Neurophysiol Clin. 2016 Feb;46(1):17-25. doi: 10.1016/j.neucli.2015.12.009. Epub 2016 Feb 26.
10
Rhythmic delta activity represents a form of nonconvulsive status epilepticus in anti-NMDA receptor antibody encephalitis.节律性δ活动是抗 N-甲基-D-天冬氨酸受体抗体脑炎的一种非惊厥性癫痫持续状态形式。
Epilepsy Behav. 2011 Feb;20(2):392-4. doi: 10.1016/j.yebeh.2010.11.020. Epub 2010 Dec 28.

引用本文的文献

1
First-episode psychosis in a 15 year-old female with clinical presentation of anti-NMDA receptor encephalitis: a case report and review of the literature.一名15岁女性首次发作精神病,临床表现为抗N-甲基-D-天冬氨酸受体脑炎:病例报告及文献复习
BMC Res Notes. 2016 Jul 29;9:374. doi: 10.1186/s13104-016-2180-6.
2
Autoimmune limbic encephalitis presenting as relapsing psychosis.表现为复发性精神病的自身免疫性边缘叶脑炎。
BMJ Case Rep. 2013 Aug 30;2013:bcr2013010461. doi: 10.1136/bcr-2013-010461.

本文引用的文献

1
Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy.N-甲基-D-天冬氨酸受体抗体在新发癫痫女性中的诊断价值
Arch Neurol. 2009 Apr;66(4):458-64. doi: 10.1001/archneurol.2009.5.
2
[Anti-NMDAR encephalopathy: treatment].
Rinsho Shinkeigaku. 2008 Nov;48(11):923-5. doi: 10.5692/clinicalneurol.48.923.
3
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies.抗N-甲基-D-天冬氨酸受体脑炎:病例系列及抗体作用分析
Lancet Neurol. 2008 Dec;7(12):1091-8. doi: 10.1016/S1474-4422(08)70224-2. Epub 2008 Oct 11.
4
[Anti-nMDA receptor encephalitis--clinical manifestations and pathophysiology].[抗N-甲基-D-天冬氨酸受体脑炎——临床表现与病理生理学]
Brain Nerve. 2008 Sep;60(9):1047-60.
5
Anti-NMDA receptor encephalitis in Japan: long-term outcome without tumor removal.日本的抗N-甲基-D-天冬氨酸受体脑炎:未切除肿瘤的长期预后
Neurology. 2008 Feb 12;70(7):504-11. doi: 10.1212/01.wnl.0000278388.90370.c3. Epub 2007 Sep 26.
6
Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.与卵巢畸胎瘤相关的副肿瘤性抗N-甲基-D-天冬氨酸受体脑炎
Ann Neurol. 2007 Jan;61(1):25-36. doi: 10.1002/ana.21050.