Pusat Perubatan Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia
Hospital Ampang, Selangor, Malaysia.
Clin Med (Lond). 2017 Oct;17(5):436-438. doi: 10.7861/clinmedicine.17-5-436.
We describe a case of a young lady with anti-NMDA (N-methyl-D-aspartate) receptor encephalitis, who initially presented with status epilepticus. Her seizures and orofacial dyskinesia were refractory to four anticonvulsants. She received intravenous immunoglobulin and a left ovarian tumour (an associated feature) was resected. However, her outcome was poor because of delayed treatment, autonomic dysfunction and complications of prolonged hospitalisation. This case highlights the importance of an early recognition of this rare but increasingly recognised disease.
我们描述了一例抗 NMDA(N-甲基-D-天冬氨酸)受体脑炎的年轻女性患者,她最初表现为癫痫持续状态。她的癫痫发作和口面运动障碍对四种抗癫痫药物均无反应。她接受了静脉注射免疫球蛋白和左卵巢肿瘤(一种相关特征)切除术。然而,由于治疗延迟、自主神经功能障碍和长期住院并发症,她的预后不佳。这个病例强调了早期识别这种罕见但越来越被认识的疾病的重要性。