Gutch Manish, Agarwal Avinash, Amar Amrendra
Department of Internal Medicine, CSMMU, Lucknow, Uttar Pradesh, India.
J Nat Sci Biol Med. 2012 Jan;3(1):81-3. doi: 10.4103/0976-9668.95976.
Dengue is the most important mosquito-borne, arboviral infection found in tropical and sub-tropical climates. Clinical presentation varies from a severe flu-like illness to a potentially lethal dengue hemorrhagic fever. Dengue has been regarded as a nonneurotropic virus. However, there are reports describing neurological involvements in dengue virus infection. The neurological involvement in dengue virus infection includes encephalitis, acute disseminated encephalomyelitis, transverse myelitis, and Guillain-Barre syndrome. The neurological spectrum of dengue patients has been limited because of small number of case reports, paucity of imaging, and neurophysiologic studies. There are only a few isolated case reports and case series documenting acute pure motor quadriparesis in dengue fever. We report acute pure motor reversible quadriparesis due to hypokalemia. Clinicians in the endemic area should be aware of such association of acute pure motor reversible quadriparesis with dengue fever.
登革热是热带和亚热带气候中发现的最重要的蚊媒虫媒病毒感染。临床表现从严重的流感样疾病到潜在致命的登革出血热不等。登革热一直被认为是一种非嗜神经性病毒。然而，有报告描述了登革病毒感染中的神经受累情况。登革病毒感染中的神经受累包括脑炎、急性播散性脑脊髓炎、横贯性脊髓炎和吉兰-巴雷综合征。由于病例报告数量少、影像学检查和神经生理学研究匮乏，登革热患者的神经学谱一直有限。仅有少数孤立的病例报告和病例系列记录了登革热中的急性单纯性运动性四肢瘫。我们报告了一例因低钾血症导致的急性单纯性运动性可逆性四肢瘫。流行地区的临床医生应意识到急性单纯性运动性可逆性四肢瘫与登革热的这种关联。
