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第一助手节约技术机器人辅助部分肾切除术可减少热缺血时间,同时保持良好的围手术期结果。

The first assistant sparing technique robot-assisted partial nephrectomy decreases warm ischemia time while maintaining good perioperative outcomes.

机构信息

Department of Urology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

出版信息

J Endourol. 2012 Nov;26(11):1448-53. doi: 10.1089/end.2012.0129. Epub 2012 Oct 9.

Abstract

BACKGROUND AND PURPOSE

Prolonged warm ischemia time (WIT) and operative time (OT) during robot-assisted partial nephrectomy (RAPN) can adversely affect renal function and clinical outcomes. Minimizing the duration of WIT and OT is critical to achieving good results postoperatively. Our standard technique for RAPN has evolved into an intracorporeal preparation (ICP) that minimizes the reliance on the first assistant. The goal of the current study was to analyze outcomes after ICP RAPN compared with those of the standard RAPN.

PATIENTS AND METHODS

A retrospective review of all patients who underwent RAPN was performed, comparing standard vs ICP technique. The ICP approach involves tacking of preprepared sutures along the abdominal sidewall adjacent to the kidney in preparation for hemostasis and renorrhaphy before arterial clamping, the use of robotic Scanlan(®) Reliance, bulldog clamps preplaced near the hilum of the kidney, and "sliding-clip" renorrhaphy. We compared intraoperative (OT, WIT, estimated blood loss [EBL]) and pre/postoperative outcomes (serum creatinine, glomerular filtration rate [GFR], length of stay [LOS]) of RAPN between the ICP and standard approach.

RESULTS

A total of 44 consecutive RAPNs (18 ICP, 26 standard) were performed. Median nephrometry score was 7a, and mean follow-up was 13 months. Mean tumor size was 2.4 cm, and most common stage was T(1a). There was no significant difference between ICP and standard RAPN with regard to nephrometry score and stage. Mean WIT was significantly lower for the ICP vs standard RAPN (19 vs 23 min, P=0.049) as was mean OT (161 vs 204 min, P=0.027). On multivariate analysis, ICP RAPN was an independent predictor of WIT (P=0.02). There was no significant impact on preoperative and postoperative GFR for either approach. EBL and LOS were similar between the two groups.

CONCLUSIONS

The ICP RAPN leads to a significant reduction in WIT and OT while maintaining similar perioperative outcomes compared with the standard approach.

摘要

背景与目的

机器人辅助部分肾切除术(RAPN)过程中,热缺血时间(WIT)和手术时间(OT)延长会对肾功能和临床结果产生不利影响。最大限度地减少 WIT 和 OT 的持续时间对于术后取得良好效果至关重要。我们的 RAPN 标准技术已经演变为一种腔内准备(ICP)技术,最大限度地减少了对第一助手的依赖。本研究的目的是分析 ICP RAPN 后的结果与标准 RAPN 的结果。

患者与方法

对所有接受 RAPN 的患者进行回顾性分析,比较标准与 ICP 技术。ICP 方法包括在靠近肾脏的腹壁上预先打结缝线,以备在夹闭动脉前进行止血和肾缝合,使用机器人 Scanlan(®)Reliance,预先放置在肾脏门附近的牛鼻钳,以及“滑动夹”肾缝合。我们比较了 ICP 和标准方法在 RAPN 中的术中(OT、WIT、估计失血量 [EBL])和围手术期(术后血清肌酐、肾小球滤过率 [GFR]、住院时间 [LOS])结果。

结果

共进行了 44 例连续的 RAPN(18 例 ICP,26 例标准)。中位肾肿瘤评分 7a,平均随访时间为 13 个月。肿瘤平均大小为 2.4cm,最常见的分期为 T1a。在肾肿瘤评分和分期方面,ICP 和标准 RAPN 之间没有显著差异。与标准 RAPN 相比,ICP RAPN 的 WIT 明显降低(19 分钟比 23 分钟,P=0.049),OT 也明显缩短(161 分钟比 204 分钟,P=0.027)。多变量分析显示,ICP RAPN 是 WIT 的独立预测因素(P=0.02)。两种方法对术前和术后 GFR 均无显著影响。EBL 和 LOS 在两组之间相似。

结论

与标准方法相比,ICP RAPN 可显著减少 WIT 和 OT,同时保持相似的围手术期结果。

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