特应性作为儿童甲状腺自身免疫的危险因素。

Atopy as a risk factor for thyroid autoimmunity in children.

机构信息

Department of Pediatrics, Second University of Naples, Italy.

出版信息

J Biol Regul Homeost Agents. 2012 Jan-Mar;26(1 Suppl):S9-14.

Abstract

Recently, there has been considerable interest in the relationship between allergic and autoimmune diseases. We evaluated the prevalence of thyroid autoimmunity in 566 children affected by atopic dermatitis (AD), urticaria, rhinitis, chronic cough, and asthma. Our results suggest that allergy and autoimmunity can be two potential outcomes of dysregulated immunity. It is tempting to speculate that NK Th2 cells can favour asthma onset and at the same time improve thyroid autoimmunity.

摘要

最近，人们对过敏和自身免疫性疾病之间的关系产生了浓厚的兴趣。我们评估了 566 名患有特应性皮炎（AD）、荨麻疹、鼻炎、慢性咳嗽和哮喘的儿童的甲状腺自身免疫患病率。我们的研究结果表明，过敏和自身免疫可能是免疫失调的两种潜在结果。人们不禁推测 NK Th2 细胞可以促进哮喘的发生，同时改善甲状腺自身免疫。