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类风湿关节炎患者髋关节的快速破坏性关节病

Rapidly destructive arthropathy of the hip joint in patients with rheumatoid arthritis.

作者信息

Yun Ho Hyun, Song Seung Yeop, Park Sung Bum, Lee Jee Wun

机构信息

Department of Orthopaedic Surgery, Seoul Veterans Hospital, Seoul, Republic of Korea.

出版信息

Orthopedics. 2012 Jun;35(6):e958-62. doi: 10.3928/01477447-20120525-42.

Abstract

This article describes 3 patients with rheumatoid arthritis in which hip joint conditions were similar to rapidly destructive arthropathy of the hip joint. The patients had the following additional characteristics: (1) age at diagnosis was comparatively older; (2) rheumatoid arthritis had an onset after age 40 years; (3) severe rheumatoid arthritis was present in >4 major joints; (4) long-term steroids and disease-modifying antirheumatic drugs were taken due to the high activity of rheumatoid arthritis; and (5) patients were underweight, with body mass indexes <20 kg/m(2).Rapidly destructive arthropathy of the hip joint rarely occurs in osteoarthritis, avascular necrosis of the femoral head, and rheumatoid arthritis. Clinically, rapidly destructive arthropathy of the hip joint occurs in elderly patients who report severe pain but have a relatively preserved range of motion. Typical radiologic changes in rapidly destructive arthropathy of the hip joint are rapid destruction, resorption, or subluxation of the femoral head, destruction of the acetabulum, and minimal spur formation developing 6 to 12 months after symptom onset. Destruction of the hip joint in rheumatoid arthritis occurs in the sequence of depression, flattening, and loss, and commonly progresses gradually. When patients with rheumatoid arthritis report persistent and severe pain in the hip joint with no specific cause, rapidly destructive arthropathy of the hip joint must be identified through repetitive follow-up radiographic observations.

摘要

本文描述了3例类风湿关节炎患者,其髋关节状况类似于髋关节快速破坏性关节病。这些患者具有以下额外特征:(1)诊断时年龄相对较大;(2)类风湿关节炎发病于40岁之后;(3)4个以上主要关节存在严重类风湿关节炎;(4)由于类风湿关节炎活动度高而长期服用类固醇和改善病情抗风湿药物;(5)患者体重过轻,体重指数<20kg/m²。髋关节快速破坏性关节病在骨关节炎、股骨头缺血性坏死和类风湿关节炎中很少发生。临床上,髋关节快速破坏性关节病发生在报告严重疼痛但活动范围相对保留的老年患者中。髋关节快速破坏性关节病的典型放射学变化是股骨头快速破坏、吸收或半脱位、髋臼破坏以及症状出现6至12个月后出现最小限度的骨刺形成。类风湿关节炎中髋关节的破坏按凹陷、变平和丢失的顺序发生,且通常逐渐进展。当类风湿关节炎患者报告髋关节持续且严重疼痛而无特定原因时,必须通过重复的随访影像学观察来识别髋关节快速破坏性关节病。

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