Dimitrov Stoimen, Gerganov Georgi, Bogdanova Simona, Hristova Svetlana, Moraliyska Rosina, Dimitrov Svetoslav, Apostolova Zhaklin, Simeonova Desislava, Shivacheva Tanya, Georgiev Tsvetoslav
Faculty of Medicine, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.
Clinic of Rheumatology, University Hospital "St. Marina", Varna, Bulgaria.
Reumatologia. 2024;62(2):134-141. doi: 10.5114/reum/186977. Epub 2024 Apr 30.
Rapidly destructive coxopathy (RDC) is a rare type of coxarthritis marked by swift deterioration of the hip joint. Although its cause remains unclear, several pathophysiological mechanisms are proposed. To comprehensively analyze this poorly understood condition, a literature search was conducted focusing on associations of bilateral RDC and rheumatoid arthritis (RA). The problem of long-standing RA, bilateral RDC with a febrile episode that preceded a rapid decline in mobility and severe hip pain, with radiological assessment confirmed bilateral hip destruction, was presented. Rapidly destructive coxopathy, especially when linked to RA, poses diagnostic and therapeutic challenges. Our review confirmed by the clinical picture emphasizes the need for vigilance in RA patients with hip involvement and calls for further research to understand RDC's mechanisms and enhance clinical care.
快速破坏性关节病(RDC)是一种罕见的髋关节炎类型,其特征是髋关节迅速恶化。尽管其病因尚不清楚,但已提出了几种病理生理机制。为了全面分析这种了解甚少的病症,我们进行了一项文献检索,重点关注双侧RDC与类风湿关节炎(RA)的关联。文中介绍了一名患有长期RA的患者,出现双侧RDC,伴有发热,随后 mobility 迅速下降且髋关节剧痛,经放射学评估证实双侧髋关节破坏。快速破坏性关节病,尤其是与RA相关时,会带来诊断和治疗挑战。我们通过临床表现证实的综述强调,对于髋关节受累的RA患者需要保持警惕,并呼吁进一步研究以了解RDC的机制并加强临床护理。 (注:原文中“mobility”此处翻译可能不太准确,结合语境推测可能是“活动能力”之类的意思,但按要求保留原文未准确翻译)